The effects of carbamazepine on resting metabolic rate and thyroid function in depressed patients

Differences in hypothyroidism between lithium-free and -treated patients with bipolar disorders

“…The anticonvulsant mood stabilizer carbamazepine has also been reported to induce a reduction in serum thyroid hormone levels and hypothalamic -pituitary-thyroid axis function (Baumgartner et al, 1997;Herman et al, 1991). This decreased thyroid function, which is manifested primarily as a low level of thyroxine (T 4 ) and triiodothyronine (T 3 ) and elevated thyroidstimulating hormone (TSH) level, can be classified as either overt or subclinical hypothyroidism (Wenzel et al, 1974).…”

Indirect Calorimetry to Measure Metabolic Rate and Energy Expenditure in Psychiatric Populations: A Systematic Review

“…The titles and abstracts of these 2947 studies were screened and 2912 irrelevant studies were excluded, leaving 35 studies for which the full texts were assessed for eligibility. Of the remaining 35 studies, 16 were excluded, and thus, the final synthesis and review included 19 studies ( Figure 1 ) [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 ].…”

Alta prevalencia de disfunción tiroidea en pacientes psiquiátricos hospitalizados

“…Especialmente en mujeres pueden elevarse los anticuerpos antitiroideos y desarrollarse un hipotiroidismo hasta en 30% de los casos. La carbamazepina produce una disminución de hormonas tiroideas y una menor respuesta de TSH a TRH [28][29][30][31] . Con respecto a los antidepresivos, se ha reportado aumento de TSH y disminución de T3 y T4 con maprotilina, fluvoxamina y un aumento del clearence de T4 con sertralina [32][33][34][35] .…”