The effects of body weight loss and gain on arterial hypertension control: an observational prospective study

Sabaka, Peter; Dukát, Andrej; Gajdošík, Ján; Bendžala, Matej; Čaprnda, Martin; Šimko, Fedor

doi:10.1186/s40001-017-0286-5

Cited by 25 publications

(22 citation statements)

References 30 publications

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“…When the causal link between body weight and the incidence of hypertension is robustly discovered, the implication for controlling the problem of high blood pressure should be raised in the developing world. The actions related to the control of body weight through which hypertension can be restricted include lifestyle changes, nutritional intake, or pharmacological treatments (Dinh et al, 2017;Francischetti and Genelhu, 2007;Lee et al, 2004;Sabaka et al, 2017). Hence, the findings from this study meaningfully provide backgrounds for the public health policies related to the control of overweight and obesity as a solution to the prevalence of hypertension.…”

Section: Discussionmentioning

confidence: 78%

Body Weight and Hypertension Risk in a Developing Country

Dang

2017

SSRN Journal

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Abstract. This study provides a first causal inference of the link between body weight and the risk of hypertension among adults in a developing country, Vietnam. The study uses biological offspring's body weight as an instrument for exogenous changes in parents' body weight to address the potential problem of endogeneity and applies the instrumental variable approach to estimate the relationship of interest. The paper finds that on average an addition BMI unit causally increases the likelihood of being hypertensive by about 5.1-7.3% points for men and 5.6-8.2% points for women. The paper also shows that the impacts of body weight on the risk of hypertension are different with various age intervals. Furthermore, overweight or obesity causally enlarges the risk of hypertension compared to underweight or normal weight.

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Section: Discussionmentioning

confidence: 78%

Body Weight and Hypertension Risk in a Developing Country

Dang

2017

SSRN Journal

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“…Physical exercise is considered having association with the regression and even prevention of left ventricular hypertrophy (a condition of heart wall's main pumping chamber become thickening and enlargement "LVH"), (Hegde & Solomon, 2015). Other than that, there is an evidence state that weight management having positive feedback with hypertension which weight increase makes higher probability to hypertension and it vice versa, (Sabaka et al, 2017). Furthermore, the overall body weight is not the actual deal who is having a relationship with blood pressure, but the body composition.…”

Section: Resultsmentioning

confidence: 99%

A Cross-sectional Study of Nutritional Status and Cardiovascular Health Status among Housewives in Tegal Regency, Central Java

Ali

Anggita

Sugiarto³

et al. 2020

Kemas

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Unhealthy diet and physical inactivity are two major factors related to degenerative diseases such as diabetes, hypertension, cancer, and it is still growing issues that mainly occurred in developing countries like Indonesia. It is a descriptive quantitative study, aims to investigate nutritional also cardiovascular health status among housewives in Tegal Regency, Central Java. Twenty adult women (33-57 years old) were voluntary and randomly signed up. Data on body weight (kg), height (cm), waist circumference (cm), hip circumference (cm), systolic-diastolic blood pressure (mm/hg) were collected by survey and measurement techniques. IBM SPSS 21 used to perform descriptive quantitative analysis for all data. Body mass index: 35% obese, 45% pre-obese, 5% overweight, 15% ideal weight. Waist circumference: 35% low category, 65% high category. Waist-to-hip ratio: 60% at risk of chronic diseases, 35% moderate, 5% good. Blood pressure: 40% hypertension stage-two, 25% hypertension stage-one, 25% elevated, 10% normal. Pre-obese and obese have found as the current nutritional status, followed by overweight. Meanwhile, hypertension has found as the current cardiovascular health status, followed by elevated blood pressure. This novel is empirical evidence for the housewife to be more physically active, and manage the diet to improve their health status.

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“…This observation contradicted earlier findings by Sebaka et al, who evaluated the effect of body weight loss and gain on arterial hypertension control. Their study indicated that weight increase was directly proportional to poor hypertension control in obese and overweight participants [33]. The difference in observation could be due to the difference in the period of observation in the two studies.…”

Section: Discussionmentioning

confidence: 96%

Effect of Anti-Hypertensive Drugs on Blood Pressure Lowering and Renal Function

Ajulo¹,

Ajulo²,

Anietimfon³

et al. 2019

JPRI

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Aim: Study aimed at evaluating blood pressure (BP) lowering effect of antihypertensive medications and their effect on renal function. Study Design: This was a progressive observational study, evaluating the lowering effect of selected antihypertensive agents on BP and renal functions of hypertensive patients. Study Location: The study involved moderately hypertensive patients who attended Cardiology clinic and were already receiving antihypertensive drug regimen at the University of Uyo Teaching Hospital, Uyo, Akwa-Ibom state, Nigeria. University of Uyo Teaching Hospital is a tertiary healthcare facility that was established in 1999. Methods: Seventy hypertensive patients who received antihypertensive medications for at least 6 months were recruited for the study. The recruited participants were advised on adherence and were given adherence chart to record time of medication used. A 3 ml blood was collected and Omron digital BP meter was used to take three separate BP readings and the average was recorded. The blood samples were analysed in the laboratory for serum creatinine (Scr) by using Randox’s Scr and blood urea nitrogen (BUN) kits. The Scr was used to calculate the creatinine clearance (CrCl) by using Corkcroft-Gault equation. Participants were followed-up for three months consecutively. Statistical analysis was considered significant at p=.05. SPSS version 20 was used for the analysis. Results: Systolic blood pressure (SBP) reduced from 130±2.64 mmHg in phase 1 to 120±1.13 mmHg in phase 3 while CrCl increased from 82.01±4.49 ml/min to 91.62±4.35 ml/min respectively. Both SBP and BUN were higher in females (131±3.30 mmHg and 2.67±0.19 µmol/l) while CrCl was higher in males (102.06±8.91 ml/min). Amlodipine (AM) reduced SBP by 9 mmHg, Lisinopril+Hydrochlorothiazide (LH) reduced SBP by 7 mmHg and Lisinopril+Amlodipine+Hydrochlorothiazide (LAH) reduced SBP by 22 mmHg. CrCl decreased among participants on AM, LH and LAH by 0.89 ml/min, 0.01 ml/min and 8 ml/min respectively. Conclusion: Antihypertensive medications reduced SBP especially in three-drug combinations but worsened renal function.

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The effects of body weight loss and gain on arterial hypertension control: an observational prospective study

Cited by 25 publications

References 30 publications

Body Weight and Hypertension Risk in a Developing Country

Body Weight and Hypertension Risk in a Developing Country

A Cross-sectional Study of Nutritional Status and Cardiovascular Health Status among Housewives in Tegal Regency, Central Java

Effect of Anti-Hypertensive Drugs on Blood Pressure Lowering and Renal Function

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