The Effects of Alcohol on Evoked Potentials of Various Parts of the Central Nervous System of the Cat

Ethanol-Induced Alterations in Electroencephalographic Activity in Adult Males

“…These studies demon strated that ethanol both reduced some ERP amplitudes and increased latencies of long latency (>100 msec) com ponents (Salamy and Williams 1973;Porjesz and Begleiter 1975; the magnitude of these eff ects is typically greater in association cortex than in primary sensory cortex (Salamy and Williams 1973;Por jesz and Begleiter 1975. It has been sug gested that this sensitivity may reflect the complex, polysynaptic structure of association cortex (Himwich and Callison 1972;Kalant 1975). However, cortical neuEthanol-Induced Alterations in EEG Activity 369 roanatomy alone cannot adequately explain our results.…”

Auditory brain stem potentials with alcohol

“…Ethyl alcohol is known to be associated with a decrease in the amplitudes of sensory evoked potentials, particularly those originating from association areas of the cortex (Schweigerdt et al 1965;Gross et al 1966;Himwich et al 1966;DiPerri et al 1968; Lewis et al 1969Lewis et al , 1970Soveri and Fruhstorfer 1969;Begleiter et al 1972;Himwich and Callison 1972;Salamy and Williams 1973;Kalant 1974;Perrin et al 1974;Grenell 1975;Rhodes et al 1975;Obitz etal. 1977;Kopell et al 1978).…”

“…At more peripheral levels of the sensory systems the effect of alcohol is generally markedly reduced or absent (Dravid et al 1963;Schweigerdt et al 1965;Himwich et al 1966;DiPerri etal. 1968;Lewis et al 1969Lewis et al , 1970Himwich and Callison 1972;Nakai et al 1973;Salamy and Williams 1973;Rhodes et al 1975), though amplitude reductions for auditory evoked potentials have been observed as far peripherally as the inferior colliculus (DiPerri et al 1968). At present, however, it is impossible to conclude at what level of sensory transmission alcohol has its first effect, because simultaneous recordings of evoked potentials from throughout the brain have not been performed.…”

The Pharmacology of Sedative/Hypnotics, Alcohol, and Anesthetics: Sites and Mechanisms of Action

“…More specifically, ethanol has been described as having unique EEG effects (see reviews by HIMWICH and CALLISON, 1972;BEGLEITER and PLATZ, 1972;PERRIN et aI., 1974). In low doses, the EEG frequency spectrum shifts to higher frequencies ("activation") (see, e.g., HADJI-DIMO et aI., 1968;SAUERLAND and HAR-PER, 1970).…”