The effects of acute exercise on serum adiponectin and resistin levels and their relation to insulin sensitivity in overweight males

Abstract

The purpose of this study was to investigate the effects of a submaximal aerobic exercise bout on adiponectin and resistin levels as well as insulin sensitivity, until 48 h post-exercise in healthy overweight males. Nine subjects performed an exercise bout at an intensity corresponding to approximately 65% of their maximal oxygen consumption for 45 min. Adiponectin, resistin, cortisol, insulin, glucose and insulin sensitivity were measured prior to exercise, immediately after exercise as well as 24 and 48 h after exercise. Data were analyzed using repeated measures ANOVA while Pearson's correlations were performed to identify possible relationship among the assessed variables. There were no significant differences for adiponectin (lg ml À1 ) [pre Insulin sensitivity increased and insulin concentration decreased significantly only immediately after exercise. Furthermore, no significant correlations were observed among the variables assessed except for the expected between insulin level and insulin sensitivity. These results indicate that a submaximal aerobic workout does not result in significant changes in adiponectin and resistin up to 48 h post-exercise. Furthermore, it appears that adiponectin or resistin is not associated with insulin sensitivity.

Acute Aerobic Exercise and Plasma Levels of Orexin A, Insulin, Glucose, and Insulin Resistance in Males With Type 2 Diabetes

“…In their investigation, nine obese males were subjected to one session of aerobic exercise for 45 minutes at approximately 65% of maximal oxygen uptake. They observed that insulin resistance index dropped and insulin concentration decreased immediately after the activity (27). In agreement with our findings, Rodnick et al reported that an aerobic exercise at 60% -70% of VO 2max for 30 -60 minutes had no effect on glucose tolerance test in subjects with type 2 insulin-resistant diabetic (28).…”

“…The importance of this issue is due to the role of OXA in maintaining the hypothalamic sensitivity of insulin (26).Our results also showed an insignificant reduction in insulin levels and insulin resistance. These findings are inconsistent with the results of Jamurtas et al (27). In their investigation, nine obese males were subjected to one session of aerobic exercise for 45 minutes at approximately 65% of maximal oxygen uptake.…”

Adipose Tissue as an Endocrine Organ

“…In most studies, one single exercise could not show acute influence on the plasma adiponectin level, no matter the duration of exercise or whether the subjects are healthy or obese [84,[86][87][88][89]. However, an article published in 2010 reported that both high and low intensity anaerobic exercise could elevate blood adiponectin level in obese men [90], which is similar to the result of another report in 2006 using healthy men with anaerobic exercise [91].…”

Factors determining the risk of the metabolic syndrome: is there a central role for adiponectin?

“…56 Regardless of the type of physical activity, adiponectin levels did not change up to 48 h post a single submaximal cycling exercise session. 57,58 A 24-week endurance training program too had limited effect. 59 However, adiponectin resistance did improve following a 4-month resistance and endurance exercise program, independent of the change in body composition.…”