The effectiveness of transcutaneous electrical nerve stimulation in the management of patients with complex regional pain syndrome: A randomized, double-blinded, placebo-controlled prospective study

Bilgili, Adem; Çakır, Tuğrul; Doğan, Şebnem Koldaş; Erçalık, Tülay; Filiz, Meral Bilgilisoy; Toraman, Füsun

doi:10.3233/bmr-160667

Cited by 45 publications

(36 citation statements)

References 29 publications

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“…In a study conducted by Bilgili et al that examined the effects of TENS on the pain, joint range of motion (ROM), and edema of pain syndrome patients, the subjects were randomly divided into groups to examine treatment results. The researchers reported that, according to the results of the study, pain and edema decreased, while joint ROM increased in the experimental group that received TENS therapy12 ) .…”

Section: Discussionmentioning

confidence: 96%

Edema and pain reduction using transcutaneous electrical nerve stimulation treatment

Choi

Lee

2016

J Phys Ther Sci

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[Purpose] The purpose of this study was to investigate the impact on the edema and pain when applying transcutaneous electrical nerve stimulation. [Subjects and Methods] Eleven patients who were diagnosed with lymphedema were selected as the subjects of the study. The experimental group received transcutaneous electrical nerve stimulation treatment on edema regions three times per week for four weeks. Surface tape measurement was used to measure changes in lower extremity edema. Pain intensity was measured using the visual analog scale. [Results] The edema decrements in the experimental group were significantly larger than those in the control group. The pain decrements in the experimental group were significantly larger than those in the control group. [Conclusion] In conclusion, application of transcutaneous electrical nerve stimulation was confirmed to be effective in reducing edema and pain.

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Section: Discussionmentioning

confidence: 96%

Edema and pain reduction using transcutaneous electrical nerve stimulation treatment

Choi

Lee

2016

J Phys Ther Sci

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“…[20][21][22][23][24] Another interesting non-pharmacological approach used in pain rehabilitation is transcutaneous electrical nerve stimulation (TENS). [25][26][27] Low-frequency TENS (<10 Hz) activates descending pain inhibition systems (conditioned pain modulation [CPM]) and promotes the release of endogenous opioid mechanisms that can markedly reduce pain symptoms. [27][28][29][30][31][32] The combination of tDCS and TENS have been proposed by previous authors, due to their potential synergetic effect on pain.…”

Section: Introductionmentioning

confidence: 99%

<p>Combining Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to Relieve Persistent Pain in a Patient Suffering from Complex Regional Pain Syndrome: A Case Report</p>

Houde¹,

Harvey²,

Labrecque³

et al. 2020

JPR

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Purpose: Complex regional pain syndrome (CRPS) is a rare neuropathic pain condition characterized by sensory, motor and autonomic alterations. Previous investigations have shown that transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) can alleviate pain in various populations, and that a combination of these treatments could provide greater hypoalgesic effects. In the present case report, we describe the effect of tDCS and TENS treatment on pain intensity and unpleasantness in a patient suffering from chronic CRPS. Results: The patient was a 37-year-old woman, suffering from left lower limb CRPS (type I) for more than 5 years. Despite medication (pregabalin, tapentadol, duloxetine), rehabilitation treatments (sensorimotor retraining, graded motor imagery) and spinal cord stimulation (SCS), the participant reported moderate to severe pain. Treatments of tDCS alone (performed with SCS turned off during tDCS application, 1 session/day, for 5 consecutive days) did not significantly decrease pain. Combining tDCS with TENS (SCS temporarily turned off during tDCS, 1 session/day, for 5 consecutive days) slightly reduced pain intensity and unpleasantness. Discussion: Our results suggest that combining tDCS and TENS could be a therapeutic strategy worth investigating further to relieve pain in chronic CRPS patients. Future studies should examine the efficacy of combined tDCS and TENS treatments in CRPS patients, and other chronic pain conditions, with special attention to the cumulative and long-term effects and its effect on function and quality of life.

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“…Picarelly et al 96 have used high frequency transcranial magnetic stimulation applied to this region in CRPS type I patients and have shown pain decrease during a period of 10 consecutive sessions, with improvement in affective pain components. Peripheral stimulation with surface electrodes (TENS) seems to be more effective when associated to exercises 97 . However, physical treatments, including exercises, mental simulation of movements (motor imagery), mirror therapy, manual lymphatic drainage, sensory discrimination training, stellate ganglion block with low intensity ultrasound or the use of pulsed electromagnetic fields have not shown clinically significant effects on these patients 98 .…”

Section: Complex Regional Pain Syndromementioning

confidence: 99%

Physical rehabilitation to treat neuropathic pain

Souza¹,

Carqueja

Baptista³

2016

Revista Dor

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The effectiveness of transcutaneous electrical nerve stimulation in the management of patients with complex regional pain syndrome: A randomized, double-blinded, placebo-controlled prospective study

Abstract: The addition of TENS to the physical therapy program was seen to make a significant contribution to clinical recovery in CRPS Type 1.

Cited by 45 publications

References 29 publications

Edema and pain reduction using transcutaneous electrical nerve stimulation treatment

Edema and pain reduction using transcutaneous electrical nerve stimulation treatment

<p>Combining Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to Relieve Persistent Pain in a Patient Suffering from Complex Regional Pain Syndrome: A Case Report</p>

Physical rehabilitation to treat neuropathic pain

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