The effectiveness of steroid treatment in nasal polyposis

Mepolizumab, a humanized anti–IL-5 mAb, as a treatment option for severe nasal polyposis

“…The primary end point of this study was the reduction in NP score 19,20 at 8 weeks after the first dosing (1 month after the second dose). This total polyp score (TPS) is the sum of the right and left nostril scores, as evaluated by means of nasal endoscopy.…”

Diffuse Nasal Polyposis and Endonasal Endoscopic Surgery: Long‐Term Results, a 65‐Case Study

“…However, even if an intermittent course of oral steroids associated with long‐term administration of topical steroids is highly effective in relieving symptoms, some refractory and uncontrolled cases of nasal polyposis warrant a surgical procedure to improve the quality of life of patients. Nevertheless, the timing and type of the surgical technique is also still a controversial subject, 6–8 as several series have been published with good results after treatment with topical steroids or a combination of oral steroids alternating with topical steroids 9–14 . The present prospective study aims at assessing the efficacy of a standardized surgical procedure.…”

Effect of glucocorticoids on nasal polyposis, with detection of inflammatory response by measurement of nitric oxide levels in nasal polyp tissue

“…After treatment, six patients (13.3 per cent) had stage 3 disease, 24 (53.3 per cent) had stage 2 and 15 (33.3 per cent) had stage 1. 19 The second part of our study assessed changes in inflammatory response by measuring NO levels in nasal polyposis tissue. There was a statistically significantly improvement in patients treated with oral and combined corticosteroid, compared with baseline values.…”