Diffuse Nasal Polyposis and Endonasal Endoscopic Surgery: Long‐Term Results, a 65‐Case Study

Dufour, Xavier; Bedier, A.; Ferrié, J.-C.; Gohler, Catherine; Klossek, Jean‐Michel

doi:10.1097/01.mlg.0000147933.14014.12

Cited by 34 publications

(22 citation statements)

References 26 publications

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“…Most authors agree on the fact that management of NP should be based primarily on a strictly medical approach, to be completed by surgery only in the case of corticosteroid failure [9,11,12]. The results of the present study show that combined surgery and corticosteroid therapy is effective in the treatment of severe NP, producing significant and long-term improvements in symptoms and in the size of nasal polyps [8,13]. A significant improvement in symptoms (p B/0.001) occurred during the first months after surgery.…”

Section: Discussionsupporting

confidence: 59%

Evaluation of the surgical treatment of nasal polyposis. II: Influence of a non-specific bronchial hyperresponsiveness

Bonfils

Avan

2007

Acta Oto-Laryngologica

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Section: Discussionsupporting

confidence: 59%

Evaluation of the surgical treatment of nasal polyposis. II: Influence of a non-specific bronchial hyperresponsiveness

Bonfils

Avan

2007

Acta Oto-Laryngologica

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“…Facial pain decreased in reverse order (Table 1) also re ecting EPOS 2012 guidelines (26) where the importance of facial pain as who detected no signi cant di erences in the VAS score for nasal congestion, nasal discharge and smell impairment among CRSwNP, CRSwNP-A, and CRSwNP-AA patients (33,34) . In contrast to our data, Alobid et al could not nd signi cant di erences between aspirin-tolerant and intolerant NP patients with asthma, in terms of nasal polyp size (35) .…”

Section: Discussionmentioning

confidence: 52%

Eicosanoid imbalance correlates in vitro with the pattern of clinical symptoms of Samter ́s triad

Forster¹,

Strathmann²,

Schafer³

et al. 2013

Rhin

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SummaryBackground: Hypersensitivity to non-steroidal anti-in ammatory drugs (NSAIDs) is often associated with chronic rhinosinusitis (CRS), nasal polyps (CRSwNP) and asthma, together known as Samter´s triad. The disease is characterised by eicosanoid imbalance. In our study, we determined clinical and laboratory parameters in respect of three groups of patients: 1) CRSwNP, 2) CRSwNP and asthma (CRSwNP-A), and 3) CRSwNP with asthma and NSAID-triggered hypersensitivity (CRSwNP-AA). Our main goal was to improve the characterisation of the stages of development in Samter´s triad, pointing to the homogeneous or heterogeneous course of disease. Methodology:Forty-three patients (10 CRSwNP, 14 CRSwNP-A, 19 CRSwNP-AA) and 10 control subjects were included in the study. Nasal assessment using the CRS visual analogue score, endoscopy-and computer tomography scores, allergy tests, analysis of sinus surgeries, asthma severity and in vitro functional eicosanoid tests (FET) with peripheral blood leucocytes were performed. Results:The scores re ecting CRS symptoms such as nasal congestion, nasal discharge and smell impairment di ered between the patients groups re ecting the severity of disease (CRSwNP-AA > CRSwNP-A > CRSwNP). Eicosanoid imbalance correlated with nasal congestion, nasal discharge and loss of smell. Conclusion:The data presented support the hypothesis of the continuous development of NSAID-triggered hypersensitivity, culminating in Samter's triad.

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“…In this study a maximum score was seen for nasal obstruction in both group 1 (6.80) and group 2 (6.77), followed by nasal discharge, sneezing, facial pain of 3.87, 3.17 and 4.20 respectively Similar results have been reported by Dufour X et al, Poetkar DM et al also reported similar results. 34,35 Magdy et al and Kakkar V et al, also reported results in a similar manner with a little difference in their scores. 7,9 Postoperative visual analog scale and diagnostic nasal endoscopy scores…”

Section: Preoperative Visual Analog Scale Scores and Diagnostic Nasalmentioning

confidence: 54%

Comparative study of conventional versus microdebrider assisted endoscopic sinus surgery in sinonasal polyposis

Ghera

Munjal

Chopra

2016

Int J Otorhinolaryngol Head Neck Surg

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INTRODUCTIONSinonasal polyp refers to edematous projections of nasal mucosa extending through nasal cavity and paranasal sinuses. Prevalence is 4% in general population. 1 Functional endoscopic sinus surgery, conventional or with powered instruments is standard surgical modality in sinonasal polyposis refractive to medical therapy. Microdebriders are the most commonly used powered instruments in endoscopic sinus surgery and continues to evolve in rhinologic surgery. 2 The aim of study was to evaluate the utility of microdebrider in endoscopic sinus surgery versus conventional instruments and to compare ABSTRACT Background: Functional endoscopic sinus surgery, conventional or with powered instruments is the standard surgical modality in sinonasal polyposis refractive to medical therapy. The recent modality, microdebrider assisted endoscopic sinus surgery offers better therapeutic approach for patients when compared to endoscopic sinus surgery with the conventional instruments. The objective was to evaluate the utility of microdebrider in endoscopic sinus surgery versus conventional instruments and to compare the intraoperative and postoperative results in both the methods. Methods: A prospective, randomized, comparative study was conducted on 30 patients with bilateral sinonasal polyposis. The subjects were selected by applying all the inclusion and exclusion criteria and divided into two groups i.e. the right and left side of nose were operated and compared for efficacy of microdebrider and conventional instruments. Each patient served as his or her own control. This study emphasizes the utility of microdebrider. It compares the intraoperative and postoperative results in the conventional and microdebrider assisted endoscopic sinus surgery. Results: The intraoperative mean blood loss and duration of surgery were significantly higher in the conventional group (p-value <0.001) as compared to microdebrider group. Postoperative symptom and endoscopy scores (discharge, scarring, crusting and polyp recurrence) were significantly higher in the conventional group (p-value <0.001) as compared to the microdebrider group in 6 months follow up. Conclusions: Microdebriders are more effective as compared to conventional endoscopic sinus surgery due to lesser intraoperative bleeding (relatively bloodless) and duration of surgery, better postoperative endoscopic and symptom scores, combine cutting and suction in a single tool, enabling accurate and precise tissue removal without damaging the surrounding mucosa , less scarring/synechiae, fewer complications.

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Diffuse Nasal Polyposis and Endonasal Endoscopic Surgery: Long‐Term Results, a 65‐Case Study

Abstract: Endoscopic sphenoethmoidectomy is indicated for nasal polyposis refractory to intensive medical management with a good improvement of patient's quality of life.

Cited by 34 publications

References 26 publications

Evaluation of the surgical treatment of nasal polyposis. II: Influence of a non-specific bronchial hyperresponsiveness

Evaluation of the surgical treatment of nasal polyposis. II: Influence of a non-specific bronchial hyperresponsiveness

Eicosanoid imbalance correlates in vitro with the pattern of clinical symptoms of Samter ́s triad

Comparative study of conventional versus microdebrider assisted endoscopic sinus surgery in sinonasal polyposis

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