The Effectiveness of Cinnamomum zeylanicum, Punica granatum Flower and Capsicum annuum Extracts Against Parascaris equorum Infective Larvae

Abstract

Recent investigations have shown that plants with medicinal peculiarities as good alternative to anthelmintics for livestock. In this study, the anthelmintic effects of three medicinal herbs (Cinnamomum zeylanicum, Punica granatum flower and Capsicum annuum) were screened in vitro against the infective larvae of Parascaris equorum. The recovered larvae of the parasite were exposed to four concentrations (50, 75, 100 and 125 mg/mL) of the extracts and then they examined for the viability at 0, 10, 20, 30 and 40 minutes after the challenge. The results revealed that all the concentrations of each plant extract had anthelmintic effects on P. equorum larvae. Also, the statistics indicated that there were significant interactions between the concentration of the extracts and time of exposure on the number of viable larvae. In addition, C. annuum extract seemed to be a strong potency to kill larvae at all concentrations from the beginning of the experiment. These results confirmed that those herbal extracts possess good antiparasitic effects against infective larvae of P. equorum and thus could be considered in anthelminthic treatment strategies.

Biological activity of phytoconstituents isolated from Cinnamomum zeylanicum and Punica granatum

“…Effect of C and extracts on . zeylanicum P.granatum cell line functional properties like anti helminthic, antifungal activity and curative effect (Rakhshandehroo et al, 2016;Shahina et al, 2018;Orhan et al, 2007). Phenolic compounds which are present in plants are responsible for a variety of pharmacological activity (Kumar and Pandey, 2013).…”

Therapeutic Potential and Safety of the Cinnamomum zeylanicum Methanolic Extract Against Chronic Toxoplasma gondii Infection in Mice

“…(2021) have reported that treating mice with Trichinella spiralis infection with C. zeylanicum displayed a significant reduction in the viability of larvae and adult worms of T. spiralis ( Salama et al., 2021 ). In an investigation conducted by Rakhshandehroo et al. (2016) , the findings showed that C. zeylanicum at concentrations of 50–125 mg/ml displayed potent anti-parasitic effects on infective larvae of Parascaris equorum after 10–40 min of incubation ( Rakhshandehroo et al., 2016 ).…”

“…In an investigation conducted by Rakhshandehroo et al. (2016) , the findings showed that C. zeylanicum at concentrations of 50–125 mg/ml displayed potent anti-parasitic effects on infective larvae of Parascaris equorum after 10–40 min of incubation ( Rakhshandehroo et al., 2016 ). Jorjani et al.…”

Chile (Capsicum spp.) as Food-Medicine Continuum in Multiethnic Mexico

“…(1) Certain infectious or parasitic diseases: antibacterial and antimicrobial [96,116]; the Pimas of Sonora use it as antibacterial [96]; Nematicide [10,117]: the Pimas of Sonora use it as a nematicide [96]; Fever: in Santo Domingo Petapa and Santa María Petapa, the Zapotecs of the Isthmus to relieve fever [61]; the korí chókame (black chile) of the Raramuris is used to prepare a tea to relieve fever [97] 4) Diseases of the visual system [61,112,114]: the Mestizos of Querétaro State use it to relieve an eye infection by applying a crushed quipín chile (C. annuum var. glabriusculum) [119]; in Santo Domingo Petapa and Santa María Petapa, the Zapotecs of the Isthmus apply chile leaves for eye problems [61]; Tenek of San Luis Potosí use it to cure eye problems [29].…”