The effect of Zymomonas mobilis culture on experimental Schistosoma mansoni infection

Santos, Juliana de Fátima Macedo; Vasconcelos, J. L. A.; Souza, Joelma Rodrigues de; Coutinho, Eridan de Medeiros; Montenegro, Sílvia Maria Lucena; Azevedo-Ximenes, E.

doi:10.1590/s0037-86822004000600015

Cited by 29 publications

(13 citation statements)

References 6 publications

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“…These results are similar to the study of Mohamed et al (29) and Zowail et al (30) who proved the protective and curative effects of useful bacteria in mice models against infection of Schistosoma mansoni (29)(30)(31). Many strains of probiotics, like Zymomonas mobilis 1*10 9 CFU/ml, when administrated by mouth provoked minor defense reaction, in mice against S. mansoni by providing prevention in treated animals (31,32). When Lactobacillus sporogenes used orally at a certain dose, for a long time,since the beginning of the infestation with S. mansoni, minimized impairment of DNA, improves liver and gut deterioration, therefore weakened adult together with ova numbers (29).…”

Section: Discussionsupporting

confidence: 86%

“…Moreover, bacterial output holds anthelmintic influence that might decrease maliciousness of numerous protozoa and helminthic illness (28). These results are similar to the study of Mohamed et al (29) and Zowail et al (30) who proved the protective and curative effects of useful bacteria in mice models against infection of Schistosoma mansoni (29)(30)(31). Many strains of probiotics, like Zymomonas mobilis 1*10 9 CFU/ml, when administrated by mouth provoked minor defense reaction, in mice against S. mansoni by providing prevention in treated animals (31,32).…”

Section: Discussionsupporting

confidence: 75%

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Effect of probiotic acidophilus plus against infection with secondary hydatid disease in BALB /c mice

Yousif¹,

Ali²

2020

IJVS

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The current study investigated the effect of acidophilus plus probiotic in the immune activities in mice to infestation with the cystic echinococcosis. Two dilutions of the probiotic bacteria 9*10 6 /0.1 ml, 30*10 3 /0.1 ml CFU were used, by intraperitoneally injection in the experimental animals, pre and post infections with protoscoleces of Echinococcus granulosus. Before infection remedy comprised injection by acidophilus plus twice with 72 hours interval, on the seventh day, animals were injected with protoscoleces intraperitoneally, after infection remedy implicated injection of animals with protoscoleces of Echinococcus protoscoleces first, next to 72 hours, probiotics were inoculated intraperitoneally. Many criteria were taken into consideration including, numbers, weights, diameters and percentage reduction of hydatid cysts of treated mice in contrast to the animals infested with only. The study showed a decline in cysts including their diameter, weighting, digit, accompanied by increasing the percentage reduction of hydatid cysts in treated mice, the highest percentage reduction was 98.03%, at both dilutions, 6 months post infection, and the minimum cysts number was 0.8 in comparison with the control group 39.4, with significant difference, in the same experiment. The minimum cysts weight was 0.0104 gm, 6 months post infection at the dilution 9*10 6 /0.1 ml CFU, compared with the control group 0.442 gm. The smallest cysts diameter was 0.057 mm in comparison with the control group 0.882 mm at dilution 9*10 6 /0.1 ml CFU, 6 months post infection. Acidophilus plus it may well be deduced that probiotic bacteria can be used as medicinal and remedial method against infection with hydatidosis.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 75%

Effect of probiotic acidophilus plus against infection with secondary hydatid disease in BALB /c mice

Yousif¹,

Ali²

2020

IJVS

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“…Probiotics, including species of Lactobacillus and Bifidobacterium (Butel, 2014 ), are thought to protect against infection by competing with pathogens for space and resources, modulating the host immune system, and producing antimicrobial peptides (Corr et al, 2009 ). Although studies investigating the effects of probiotics on helminth infections have yielded conflicting results, with studies showing that probiotics can reduce helminth burdens (Stefanski and Przyjalkowski, 1965 , 1966 ; Bautista-Garfias et al, 1999 , 2001 ; Santos et al, 2004 ; Basualdo et al, 2007 ; Martínez-Gómez et al, 2009 , 2011 ; Chiodo et al, 2010 ; Oliveira-Sequeira et al, 2014 ), increase susceptibility to helminths (Dea-Ayuela et al, 2008 ; Reynolds et al, 2014 ), or have no effect on helminth burden (de Waard et al, 2001 ; Verdú et al, 2004 ), the majority of published studies have found a decrease in helminth burdens with probiotic administration. This suggests that certain probiotic species may help protect against helminth infection, though the underlying mechanisms remain unclear.…”

Section: Applications Of Understanding Parasite-microbiota Interactiomentioning

confidence: 99%

Parasite-Microbiota Interactions With the Vertebrate Gut: Synthesis Through an Ecological Lens

2018

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The vertebrate gut teems with a large, diverse, and dynamic bacterial community that has pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions, these microbes share their habitat with a similarly dynamic community of eukaryotes (helminths, protozoa, and fungi), many of which are well-known parasites. Both parasites and the prokaryotic microbiota can dramatically alter the physical and immune landscape of the gut, creating ample opportunities for them to interact. Such interactions may critically alter infection outcomes and affect overall host health and disease. For instance, parasite infection can change how a host interacts with its bacterial flora, either driving or protecting against dysbiosis and inflammatory disease. Conversely, the microbiota can alter a parasite's colonization success, replication, and virulence, shifting it along the parasitism-mutualism spectrum. The mechanisms and consequences of these interactions are just starting to be elucidated in an emergent transdisciplinary area at the boundary of microbiology and parasitology. However, heterogeneity in experimental designs, host and parasite species, and a largely phenomenological and taxonomic approach to synthesizing the literature have meant that common themes across studies remain elusive. Here, we use an ecological perspective to review the literature on interactions between the prokaryotic microbiota and eukaryotic parasites in the vertebrate gut. Using knowledge about parasite biology and ecology, we discuss mechanisms by which they may interact with gut microbes, the consequences of such interactions for host health, and how understanding parasite-microbiota interactions may lead to novel approaches in disease control.

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“…Also Enterococcus faecalis CECT7121, a probiotic with inhibitory activity against Gram-positive and Gram-negative bacteria, possesses in vitro and in vivo larvicidal activity determining up to a 90% reduction of the number of Toxocara canis larvae in liver and lungs of laboratory mice (Basualdo et al, 2007; Chiodo et al, 2010). Zymomonas mobilis , a bacterium producer of bioethanol, was reported to provide over 60% protection from the infection of S. mansoni in mice (Santos Jde et al, 2004). …”

Section: Probiotics Against Parasitesmentioning

confidence: 99%

Interactions between parasites and microbial communities in the human gut

Berrilli¹,

Cave²,

Cavallero³

et al. 2012

Front. Cell. Inf. Microbio.

122

114

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The interactions between intestinal microbiota, immune system, and pathogens describe the human gut as a complex ecosystem, where all components play a relevant role in modulating each other and in the maintenance of homeostasis. The balance among the gut microbiota and the human body appear to be crucial for health maintenance. Intestinal parasites, both protozoans and helminths, interact with the microbial community modifying the balance between host and commensal microbiota. On the other hand, gut microbiota represents a relevant factor that may strongly interfere with the pathophysiology of the infections. In addition to the function that gut commensal microbiota may have in the processes that determine the survival and the outcome of many parasitic infections, including the production of nutritive macromolecules, also probiotics can play an important role in reducing the pathogenicity of many parasites. On these bases, there is a growing interest in explaining the rationale on the possible interactions between the microbiota, immune response, inflammatory processes, and intestinal parasites.

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The effect of Zymomonas mobilis culture on experimental Schistosoma mansoni infection

Abstract: ABSTRACT

Cited by 29 publications

References 6 publications

Effect of probiotic acidophilus plus against infection with secondary hydatid disease in BALB /c mice

Effect of probiotic acidophilus plus against infection with secondary hydatid disease in BALB /c mice

Parasite-Microbiota Interactions With the Vertebrate Gut: Synthesis Through an Ecological Lens

Interactions between parasites and microbial communities in the human gut

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