The effect of vitamin C supplementation in the last month of pregnancy on neonatal bilirubin levels; A double-blind randomized clinical trial

al-hosseini, Mojtaba Khadem; Rahideh, Seyedeh Tayebeh; Saadati, Alireza; Rahmati, Nayereh; Azadeh, F.; Janani, Leila; Shidfar, Farzad

doi:10.1016/j.ctim.2020.102359

Cited by 3 publications

(1 citation statement)

References 17 publications

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“…Thus, supplementing the daily diets with vitamin D is essential to prevent COVID-19 pneumonia with promoted psychological well-being [ 72 ]. In addition, a moderate supplementation of vitamin C through increasing the body's immunity not only can reduce the susceptibility of respiratory tract infection induced by COVID-19 [ 6 , 72 ], but also can notably reduce the neonatal bilirubin levels in the last month of pregnancy [ 73 , 74 ]. Moreover, the remote follow-up route should be set up to monitor bilirubin levels under severe quarantine and control measures to avert hyperbilirubinemia development [ 75 ].…”

Section: Available Treatments and Therapiesmentioning

confidence: 99%

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Khedmat

Mohaghegh

Veysizadeh

et al. 2021

Arch Gynecol Obstet

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Section: Available Treatments and Therapiesmentioning

confidence: 99%

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Khedmat

Mohaghegh

Veysizadeh

et al. 2021

Arch Gynecol Obstet

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Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids

Reza,

Farooqui,

Reza

et al. 2023

Stem Cell Reports

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The effect of oral use of concentrated pomegranate juice by mothers on hyperbilirubinemia in neonates under phototherapy: A randomized clinical trial

et al. 2023

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Background: Hyperbilirubinemia is a common problem in neonates that causes hospitalization. The aim of this study was to investigate the effects of concentrated pomegranate juice (CPJ) consumption by breastfeeding mothers on neonatal hyperbilirubinemia. Materials and Methods: In this open-labeled, add-on, randomized clinical trial, 86 breastfeeding mothers and their neonates were allocated into two groups. In the control group, neonates received phototherapy. Besides neonates’ phototherapy in the intervention group, their mothers received CPJ (1 tablespoon [15 g] three times a day) up to discharge. The bilirubin level was the primary outcome. The duration of phototherapy, the duration of hospital stay, and the need for exchange transfusions were secondary outcomes. Results: CPJ reduced the bilirubin level of hospitalized neonates within 48 h after consumption ( P = 0.048, standard mean difference = 0.648). It also resulted in reduced duration of hospital stay and faster discharge of the neonates. Furthermore, in 48 h after discharge, bilirubin was significantly lower in the CPJ group ( P = 0.003, partial eta squared = 0.123). Conclusion: Compared to the control group, consumption of CPJ by lactating mothers whose infants underwent phototherapy resulted in lower bilirubin levels, shorter hospital stay, and faster discharge.

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The effect of vitamin C supplementation in the last month of pregnancy on neonatal bilirubin levels; A double-blind randomized clinical trial

Cited by 3 publications

References 17 publications

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids

The effect of oral use of concentrated pomegranate juice by mothers on hyperbilirubinemia in neonates under phototherapy: A randomized clinical trial

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