The effect of various forms of alumina on the lungs of rats

King, E. J.; Harrison, C. V.; Mohanty, G. P.; Nagelschmidt, G.

doi:10.1002/path.1700690113

Cited by 36 publications

(9 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies of pneumoconioses associated with the inhalation of A1203, AlPO4, and condensed corundum furnace fume (1:1 A1203 and SiO2) by rats suggested that A1203 was the most fibrogenic (556). An emphysematous change has been observed in rabbits and rats, similar to that seen in humans following prolonged IH exposure to an industrial dust containing A1203 and SiO2 (557).…”

Section: Toxicology Of Aluminum and Its Compoundsmentioning

confidence: 95%

Aluminum in the Environment and Human Health

Sorenson¹,

Campbell²,

Tepper³

et al. 1974

Environmental Health Perspectives

View full text Add to dashboard Cite

The review of over 800 references on aluminum (Al) published since the mid-fifties covers the occurrence of Al in soil, air, water, plants and food products, as well as air and water pollution problems. In addition, the existing quality criteria, the biology and toxicology of Al, and the therapeutic and medical uses are presented. It is concluded that absorption and retention or accumulation of Al in humans occurs at lower levels of intake than had been assumed formerly. However, levels of 5 to 50 times the normal daily intake do not appear to interfere with other metabolic processes. The adverse effects of Al reported in the more recent years resulted from the inhalation or ingestion of Al in concentrations many times greater than the amounts present under normal circumstances. As in the past, there is still no need for .ncern by the public or producers of Al or its products concerning hazards to human health derived from well established and extensively used products.

show abstract

Section: Toxicology Of Aluminum and Its Compoundsmentioning

confidence: 95%

Aluminum in the Environment and Human Health

Sorenson¹,

Campbell²,

Tepper³

et al. 1974

Environmental Health Perspectives

View full text Add to dashboard Cite

show abstract

“…Of interest is the relationship between metallic aluminum and the materials t o which it is appended as it enters the respiratory tract. It has been shown that most of the aluminum is in the form of oxides, oils, or lipids (2,3,11,13,21,24); further admixture with respiratory secretions renders it difficult to assign a precise etiologic role to aluminum. The element must conceivably be coated with some substance in order to inc2Jce pathologic changes.…”

Section: Discussionmentioning

confidence: 99%

The Pulmonary Effects of Pure Aluminum

Greenberg

1977

The Bulletin of the Society of Pharmacological and Environmenta

View full text Add to dashboard Cite

“…It can lead to aggravation of medical conditions such as asthma, chronic lung disease and skin rashes. King et al (1955) studied the exposure to guinea pigs to alumina and found no harmful effects in lungs after one year.…”

Section: Introductionmentioning

confidence: 99%