The effect of transfer to a warm environment (30° C.) on the metabolic response to injury

Abstract

550 450 354 250 THE EFFECT OF TRANSFER TO A WARM ENVIRONMENT (30°C.) ON THE METABOLIC RESPONSE TO INJURY 20'C. 30°C.c I Urine N, mean ' S.E.M.

Metabolic changes.

“…In skeletal injury there is less disturbance compared with the low albumin, high a2-, and yG concentrations observed in burned patients but unexpectedly these do not appear to be affected by the severity of the injury (see also Cuthbertson, Tilstone, and Green, 1969). In fracture cases and in the rat we have also observed the effect of a temperature of 30°C in reducing the catabolism of protein and heat production (Campbell and Cuthbertson, 1967;Cuthbertson, Smith, and Tilstone, 1968;Cuthbertson and Tilstone, 1969a;Tilstone and Cuthbertson, 1970) and in reducing the fall in albumin and rise in yG globulin.…”

Energy metabolism after injury.

“…This effect of raising the ambient temperature to the thermoneutral zone is now well established in the case of burns (Caldwell, Osterholm, Sower, and Moyer, 1959;Caldwell, 1962;Caldwell et al, 1966;Barr, Birke, Liljedahl, and Plantin, 1968;Davies, Liljedahl, and Birke, 1969). However, it has now been shown that a thermoneutral ambient temperature also inhibits the 'flow' period response to fracture of a bone which does not increase the evaporative water loss from the body (Campbell and Cuthbertson, 1967;Cuthbertson, Smith, and Tilstone, 1968). Changes in food intake which occur when the environmental temperature is altered can make such experiments difficult to interpret but the effect appears to be a real one.…”

Heat loss during thoracotomy: A preliminary report

“…They did not mention surface temperatures in these patients. Cuthbertson et al (1968) from Glasgow approached the problem from another angle. They have shown that both rats and humans who are injured and who are nursed in a warm room at a temperature of 300 C. do not produce the so-called 'metabolic response to trauma'.…”