The Effect of Topical Fluoride Agents on Fluoride Uptake and Surface Morphology

Wefel, James S.; Harless, J.D.

doi:10.1177/00220345810600110301

Cited by 64 publications

(33 citation statements)

References 9 publications

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“…Even though there is evidence that the glaze is stable against strong acids [Büyükyilmaz et al, 1997b;Wefel and Harless, 1981], the reaction mechanisms of TiF 4 with the tooth surfaces and therefore the reason for the stability of the glaze and the protective effect are not definitely clarified. But it can be suggested that the titanium ion plays a decisive role.…”

Section: Discussionmentioning

confidence: 99%

Effect of Titanium Tetrafluoride and Sodium Fluoride on Erosion Progression in Enamel and Dentine in vitro

et al. 2007

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Our aim was to investigate the effect of TiF₄ solutions on mineral loss on enamel and dentine in vitro. Samples were fluoridated 1 × 5 min per day with 1.64% w/v TiF₄ or 2.2% w/v NaF solutions, each with a pH of 1.2, and then subjected to a cyclic de- and remineralization procedure for 5 days. Demineralization was performed for 6 × 10 min per day with citric acid (pH 2.3). In controls no fluoridation was performed. Mineral content was determined by longitudinal microradiography. Enamel mineral loss was markedly reduced by both fluoride solutions, but TiF₄ was significantly more effective than NaF: cumulative mineral loss on day 3 was 61.7 ± 15.0 µm in the NaF and 34.2 ± 13.1 µm in the TiF₄ group (p ≤ 0.001) compared with 121.0 ± 27.0 µm in the control group. Dentine mineral loss ceased after both TiF₄ and NaF applications (cumulative mineral loss on day 5 in controls: 61.0 ± 17.0 µm, in the TiF₄ group: 15.4 ± 13.4 µm and in the NaF group: 21.8 ± 11.8 µm). Both TiF₄ and NaF application reduced mineral loss both on enamel and dentine, which could open new possibilities for a symptomatic therapy of erosions.

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Section: Discussionmentioning

confidence: 99%

Effect of Titanium Tetrafluoride and Sodium Fluoride on Erosion Progression in Enamel and Dentine in vitro

et al. 2007

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“…Fluoride may be incorporated in a soluble (CaF2) and/or permanently bound (fluoroapatite) form. In vitro studies have shown that fluoride applications deposit a reaction product coating of CaF2 on the anatomical surface of enamel 21,22) , and that fluoride is also permanently incorporated into the enamel during application [23][24][25] . It is highly probable that CaF2 creates mineral deposition in the porous zone of enamel and increases the microhardness 26) , thereby resulting in increased bond strength.…”

Section: Discussionmentioning

confidence: 99%

Effect of Fluoride in Phosphate Buffer Solution on Bonding to Artificially Carious Enamel

Wang¹,

Shimada²,

Tagami³

2007

Dent. Mater. J.

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The purpose of the present study was to evaluate the effect of fluoride on resin bonding to artificially carious enamel. Specimens from demineralized human enamel sections were prepared using two commercially available adhesives (Clearfil SE Bond, Kuraray; Single Bond, 3M) and a composite resin (Clearfil AP-X, Kuraray) according to manufacturers' instructions. They were then immersed in phosphate buffered saline solution with varied fluoride concentrations at 0, 0.1, 0.5, 1, and 10 ppm. After immersion in each solution for one, three, or seven days, microshear bond strength was measured. The bond strengths of both adhesive systems to artificially carious enamel significantly increased after immersion in fluoridephosphate buffer solution. Based on the findings obtained, we thus proposed not to remove the white enamel lesions for bonding in the clinic. They might be preserved and treated using fluoride applications.

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“…Quantification of both the amount of fluoride in the enamel (Fjn) and the amount present as calcium fluoride on the material (Fon) have been presented in pre vious in vitro studies by Hellslrbm and Ericsson [1976], Wefel and Harless [1981], Relief et al [1981], Dijkman et al [1982b] and Gron and Caslavska [1979]. In vivo this phenomenon was studied by Larsen et al [1981], analyzing NaF-and APF-treated enamel slabs by the method of Caslavs ka etal.…”

mentioning

confidence: 99%

In vivo Investigation on the Fluoride Content in and on Human Enamel after Topical Applications

1983

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In this in vivo study the amount of fluoride present on and in human enamel was followed longitudinally for a period of 3 months. The fluoridating agents were an APF gel and the fluoridating lacquers Duraphat and Fluor Protector. The fluoride on the enamel (F_on, mainly as CaF₂) was determined by the Caslavska method. The fluoride in the enamel (F₂) was measured in five enamel layers removed by acid etching. 12 patients wore the treated enamel specimens and controls for periods of 1, 4 and 12 weeks before the Fon and F₂ determinations were made. The CaF₂ (or F_on) was lost in vivo in all three treatments at a rate of about 20 μg cm^-2 in the first week. Consequently, APF gel- and Duraphat-treated specimens lost nearly all CaF₂ in vivo in this period. The amount of CaF₂ present in the Fluor Protector case was noticeable up to 1 month. A second conclusion from this study is that the amount of acquired F^- (F₂ in a layer of 30 μm) following APF gel or Duraphat treatment was negligible after 1 week in vivo. A Fluor Protector treatment introduced an amount of acquired fluoride of 11, 14 and 15 μg cm^-2 after 1 4 or 12 weeks, respectively. This study shows that if sufficient CaF₂ is deposited on the enamel in vivo for a sufficiently long time, the amount of F∼ in the enamel can be increased significantly. Thirdly, despite the fact that during the in vivo experiments considerable amounts of CaF₂ were lost in the saliva, no measurable enrichment of control sound enamel resulted, not even in sound enamel specimens 3 mm from the treated blocks.

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The Effect of Topical Fluoride Agents on Fluoride Uptake and Surface Morphology

Abstract: Four topical fluoride agents were evaluated in vitro for their ability to form permanently bound fluoride. APF, NH4F, and Na2SnF6 formed soluble reaction products, while TiF4 did not. Surface coatings were present on those samples that showed higher levels of fluoride after washing.

Cited by 64 publications

References 9 publications

Effect of Titanium Tetrafluoride and Sodium Fluoride on Erosion Progression in Enamel and Dentine in vitro

Effect of Titanium Tetrafluoride and Sodium Fluoride on Erosion Progression in Enamel and Dentine in vitro

Effect of Fluoride in Phosphate Buffer Solution on Bonding to Artificially Carious Enamel

In vivo Investigation on the Fluoride Content in and on Human Enamel after Topical Applications

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