The Effect of the Reduced Dose of GnRH on Conception, Ovulation and Ovarian Structures in Ovsynch Program of Lactating Dairy Cows

Karaca, Fikret; Doğruer, Gökhan; Saribay, Mustafa Kemal; Ergün, Yaşar; Ateş, Cafer Tayyar

doi:10.18488/journal.ar/2016.3.3/101.3.66.72

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…Tego rodzaju rozwiązanie umożliwiało uzyskanie oszczędności rzędu 6,40 $ na krowę i 20,25 $ na ciążę (23). Dalsze redukowanie dawki GnRH do 10,5 i 5,25 µg octanu busereliny, jak również ograniczanie ilości podawanego kloprostenolu do 150 mg nie powodowało istotnych różnic w rozmiarach owulacyjnych pęcherzyków jajnikowych i płodności krów (32).…”

Section: Modyfikacje Klasycznego Programu Ovsynchunclassified

OvSynch program, its modifications and alternative hormonal programs in cow reproduction

Jaśkowski

Herudzińska

Kulus

et al. 2018

Medycyna Weterynaryjna

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The OvSynch program was formulated over 20 years ago (it consists in administering gonadoliberin on the day of starting the procedure, then injecting prostaglandin 7 days after the GnRH initial injection, and administration of GnRH two days after applying PGF2α. The procedure ends in the insemination of a female 16–20 hours after administering the final dose of the hormone) and it is commonly applied in cow reproduction management protocols. It has evolved into numerous modifications which has boosted its effectiveness. They have consisted in replacing GnRH with hCG or pLH, diversifying the time of the final injection of GnRH, which follows the prostaglandin injection, and postponing insemination after the final GnRH dose, as well as changing the dosage of the aforementioned hormones. To expedite the Ovsynch protocol, so-called PreSynch was used, which involved administering two prostaglandin injections with a 14 day interval before applying the initial GnRH dose in protocol OvSynch. The interval between the second prostaglandin injection in the PreSynch program varied (PreSynch-14, PreSynch-12, PreSynch-11, PreSynch-11 and PreSynch). The pregnancy rate can be also improved by introducing GnRH injection before starting the OvSynch program, administered 7, 6 or 4 days before the initial GnRH injection in OvSynch (G7G, G6G, G4G). Higher pregnancy rates, in comparison to the PreSynch-OvSynch program, can be obtained by applying the DoubleOvsynch protocol. In this protocol two OvSynch programs are administered in a 7-day interval. Lately, alternative programs such as DoubleSynch and EstraDoubleSynch have emerged. The DoubleSynch protocol consists in administering PGF2α in day 0, GnRH on the second day, another PGF application on the 9th day, and the second GnRH dose on the 11th day. Artificial insemination is performed in oriented time (TAI). This solution is used in order to achieve a higher percentage of pregnant cows in comparison to the PreSynch+OvSynch protocol. It also enables synchronisation of heat and ovulation, both after the first and the second hormonal treatment of GnRH. In EstraDoubleSynch protocol the second injection of GnRH at the end of the DoubleSynch program is replaced by estradiol benzoate (BE) administration on the 10th day, in order to acquire a higher level of follicle waves synchronisation and ovulation rate. Those programs applied in cow reproduction management can positively influence fertility and boost cow breeding profitability..

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Section: Modyfikacje Klasycznego Programu Ovsynchunclassified

OvSynch program, its modifications and alternative hormonal programs in cow reproduction

Jaśkowski

Herudzińska

Kulus

et al. 2018

Medycyna Weterynaryjna

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“…However, because of multiple injections and handling administered at specific times, a greater direct cost of initial treatment is incurred. The ovsynch protocol requires three hormonal injections with the GnRH responsible for approximately 70 % of the total cost in a dairy cow (Baranski et al, 2021;Karaca et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Effect of Gonadotrophin Releasing Hormone on Follicular Dynamics, Luteinising Hormone, and Progesterone Levels in Bunaji Cows

Dare,

Mamman,

Kawu

et al. 2023

FUDMAJAAT

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This study evaluated the ovarian and hormonal responses of Bunaji cows to ovsynch protocol initiated at random oestrus cycle stages. Fifteen animals were arranged into three groups and treated as follows: control (n=5), 2mL normal saline; group A (n=5), 50mg Gonadotrophin releasing hormone (GnRH) on day 0 and day 9 followed by 500mg of Prostaglandin F2 alpha (PGF2a) on day 7; and group B (n=5) 100mg of GnRH on day 0 and day 9 followed by 500mg PGF2a on day 7. Ultrasound examination of the ovaries was carried out daily from d 1 to d 9 and, thereafter every 12h until ovulation was detected. Blood sampling was carried out at 30 min intervals for 6 h following the GnRH administration for determination of serum luteinizing hormone (LH) and once daily for 12 days after the injection of the first GnRH to determine plasma progesterone concentration. The ovarian response of the treated groups showed no significant difference between the two dosages of ovsynch protocol but differed significantly between the treated and the control groups. Peak values of serum LH obtained on day 0 and day 9 of GnRH administration differed significantly (P<0.05). Plasma progesterone increased among treated groups following injection of GnRH reaching a peak on day 7 compared to control, but did not differ among treated groups. In conclusion, GnRH at 50 mg and 100 mg was able to elicit adequate LH and progesterone responses that caused the disappearance of dominant follicles and, subsequent ovulation thereby increasing the reproductive efficiency of Bunaji cows.

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The Effect of Reduced GnRH Dose on Ovulation and Follicular Dynamics in Ovsynch Programme of Pure and Bunaji-Crossbred Cows

Dare,

Mamman,

Kawu

et al. 2024

Trop Anim Health Prod

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The Effect of the Reduced Dose of GnRH on Conception, Ovulation and Ovarian Structures in Ovsynch Program of Lactating Dairy Cows

Cited by 4 publications

References 4 publications

OvSynch program, its modifications and alternative hormonal programs in cow reproduction

OvSynch program, its modifications and alternative hormonal programs in cow reproduction

Effect of Gonadotrophin Releasing Hormone on Follicular Dynamics, Luteinising Hormone, and Progesterone Levels in Bunaji Cows

The Effect of Reduced GnRH Dose on Ovulation and Follicular Dynamics in Ovsynch Programme of Pure and Bunaji-Crossbred Cows

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