The effect of the polycystic ovary syndrome and hypothyroidism on the risk of fibrocystic breast changes: a meta-analysis

Kohnepoushi, Parisa; Dehghanbanadaki, Hojat; Mohammadzedeh, Pardis; Nikouei, Maziar; Moradi, Yousef

doi:10.1186/s12935-022-02547-5

Cited by 4 publications

(5 citation statements)

References 40 publications

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“…For the normal menopausal group, the most common pathologies were also cyst (53.7%) and cystic changes (17.9%). Our results also showed a significantly higher rate of fibroadenoma in women with early menopause (p value=0.032), which is consistent with previous results (12)(13)(14).…”

Section: Discussionsupporting

confidence: 93%

“…It is also important to note that the overall rate of malignant breast masses in post-menopausal women is much higher than in women of childbearing age, which is evidence that hormonal cycles during fertility have a protective effect against malignancies (17,18). The rate of breast cysts in women who have menstrual cycles is significantly higher than in menopausal women due to the high impact of cysts on hormonal cycles (14,15). This phenomenon is significantly reduced in post-menopausal women but remains in early-menopausal women (16,17).…”

Section: Discussionmentioning

confidence: 99%

“…It is important to pay attention to the results of this study because over the past few decades, due to the increase in life expectancy and the number of postmenopausal women (14,17), the age parameter, which is one of the most important indicators of breast cancer, has increased significantly. In the present study, the rate of breast masses and malignancies was directly related to menopausal age and especially menopause at older ages.…”

Section: Discussionmentioning

confidence: 99%

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Relationship between age at menopause and breast ultrasonography results

GÜRKAN

AĞAR

DEMİRÇİVİ>³

2022

Journal of Medicine and Palliative Care

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Giriş: Kadınların yaşlanmasının doğal süreci olan menopoz, beraberinde pek çok sorunu da getirmektedir. Menopozla birlikte meme bezi dokusu kaybı hızla artar ve meme bezlerinde atrofi, dejenerasyon ve hyalinizasyona bağlı olarak büyük kayıplar meydana gelir. Ultrasonografi (USG) bu meme değişikliklerinin tespit edilmesine yardımcı olur. Bu çalışmada menopozal olgularda 40 yıl öncesi ve sonrası meme USG bulguları karşılaştırıldı. Gereç ve Yöntem: Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi Kadın Hastalıkları ve Doğum Kliniği’ne Ekim 2014-Eylül 2020 tarihleri arasında başvuran menopozal hastaların dosyaları retrospektif olarak taranarak analiz edildi. Menopoza giren hastaların yaşlarına göre 1. grup 40 yaş altı ve 2. grup 40 yaş üstü olmak üzere iki gruba ayrıldı. 1. grupta (olgu grubu) 52 hasta ve 2. grupta (kontrol grubu) 67 hasta çalışmaya dahil edildi. Bulgular: Çalışmaya katılanların yaş ortalaması 1. grupta 33.2, 2. grupta 48.6 idi. Vücut kitle indeksleri (BKİ) grup 1’de 24,8 kg/m², grup 2’de 25.1 kg/m² idi. Meme USG bulguları incelendiğinde 1. grupta kist oluşum insidansı istatistiksel olarak anlamlı derecede yüksek bulundu. 2. grup (p

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Relationship between age at menopause and breast ultrasonography results

GÜRKAN

AĞAR

DEMİRÇİVİ>³

2022

Journal of Medicine and Palliative Care

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“…Recently it is reported that PCOS was one of the etiological factors of ER-positive breast cancer [32]. The studies conducted by Moradi., et al confirms the association between fibrocystic breast changes and PCOS [33].…”

Section: Is There a Relation Between Pcos And Breast Cancer?mentioning

confidence: 74%

Hormonal Imbalance and Breast Cancer in Women

A¹,

Thomas²

2022

Act Sci wom hea

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This article investigates the relation between hormonal changes and how it leads to breast cancer. Breast cancer is continuing to be one most of the most leading cause for the death of women especially worldwide. We referred many journals and articles that are recently published to get a clear picture of the indirect relation of hormonal changes and breast cancer. The hormonal changes lead to polycystic ovarian syndrome (PCOS), which is the main reason for infertility in the present generation. PCOS is considered to be a lifestyle disease, that can cause many hazardous health condition. This article clearly explains how obesity and PCOS are related and how it leads to breast cancer. The treatment strategies that are available now a days to cure breast cancers are also discussed. The drawbacks of the treatments and drugs are merely mentioned in the last section.

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“…However, the exact cause of these changes remains unclear. Certain conditions that cause hormonal imbalances, such as polycystic ovarian syndrome (PCOS), have also been associated with an increased risk of FCCs [ 3 , 4 ]. Evaluation of FCCs is typically performed by mammography, ultrasonography, and biopsy.…”

Section: Introductionmentioning

confidence: 99%

An Interesting Imaging Presentation of a Common Benign Entity: Fibrocystic Changes in a Postmenopausal Patient

Dang¹,

Miles²,

Young³

et al. 2023

Cureus

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Fibrocystic changes (FCCs) are common, often benign, breast lesions characterized by adenosis, fibrosis, and cyst formation. These changes are believed to be associated with fluctuating hormone levels and are predominantly found in premenopausal women due to higher levels of estrogen. Certain conditions that cause hormonal imbalances, such as polycystic ovarian syndrome, have also been associated with an increased risk of FCCs. FCCs can occur in postmenopausal women on hormonal replacement therapy but are otherwise extremely rare. Although this condition is primarily considered benign, complex cysts presenting in a rare demographic warrant further evaluation beyond screening mammograms to exclude the possibility of malignancy. In this paper, we present the case of new FCCs in a postmenopausal woman and explore the radiology, histology, carcinogenic potential, treatment options, and potential contributing factors of the condition.

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The effect of the polycystic ovary syndrome and hypothyroidism on the risk of fibrocystic breast changes: a meta-analysis

Cited by 4 publications

References 40 publications

Relationship between age at menopause and breast ultrasonography results

Relationship between age at menopause and breast ultrasonography results

Hormonal Imbalance and Breast Cancer in Women

An Interesting Imaging Presentation of a Common Benign Entity: Fibrocystic Changes in a Postmenopausal Patient

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