2015
DOI: 10.1111/jcpe.12332
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The effect of the local use of chlorhexidine in surgical treatment of experimental peri‐implantitis in dogs

Abstract: It is suggested that (i) the local use of chlorhexidine has minor influence on treatment outcome, (ii) resolution of peri-implantitis following surgical treatment without the adjunctive use of local and systemic antimicrobial agents is possible and (iii) the results are influenced by implant surface characteristics.

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Cited by 52 publications
(70 citation statements)
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“…In contrast to previous studies, 36 , 44 the present results show that peri‐implantitis progression around an anodized implant surface ceased after treatment, as did additional tissue breakdown. This could be explained by the different treatment methods used in the previous studies.…”
Section: Discussioncontrasting
confidence: 99%
“…In contrast to previous studies, 36 , 44 the present results show that peri‐implantitis progression around an anodized implant surface ceased after treatment, as did additional tissue breakdown. This could be explained by the different treatment methods used in the previous studies.…”
Section: Discussioncontrasting
confidence: 99%
“…Furthermore, they exhibited the lowest overall frequency of implants/patients with treatment success (16% and 13%, respectively) and had no cases with treatment success when treatment protocols without adjunctive systemic antibiotics (groups 3 and 4) were used. The observed lack of effect of the local use of chlorhexidine on treatment outcomes reported in the study by Carcuac et al (2015) is also consistent with findings in the present investigation.…”
Section: Discussionsupporting
confidence: 95%
“…There are several plausible explanations for this finding; first, an extensive peri‐implant defect exposes a larger implant surface. Exposed surfaces, especially rough/modified surfaces, give an increase to the total microbiological load (Albouy, Abrahamsson, Persson, & Berglundh, ; Carcuac, Abrahamsson, Charalampakis, & Berglundh, ). Second, larger defects might be located deeper in the mandibular or maxillary bone, apically to the vestibulum, hampering the possibility for surgical apically positioning of the flap and thus preventing biofilm removal postsurgically.…”
Section: Discussionmentioning
confidence: 99%