As an advanced position in China's reform and opening up policy, Guangdong Province has been playing a leading role in the economic level. However, the competitiveness of cultural industry is slightly inferior and is in an important transition period. Based on the Porter Diamond model theory, the factors affecting the competitiveness of cultural enterprises are explored in this paper. Through collecting the data from 2017 to 2019 and conducting the factor analysis, the ranking of cultural competitiveness of provinces and cities in China can be obtained. The results show that: (1) Internal environment, external conditions and relevant policies and regulations play a crucial role in the competitiveness of cultural enterprises; (2) The comprehensive competitiveness of Guangdong's cultural industry ranks the fourth among the 31 provinces in China, indicating that Guangdong has the cultural competitiveness of sustainable competitive advantage, but there is still a large room for improvement; (3) The internal driving force of consumer demand in Guangdong Province is insufficient, and the government intervention should be continuously strengthened.