The effect of the age of the recipients on pregnancy rates following donor-oocyte replacement

Check, Jerome H.; Askari, Hasan; Choe, Jonggeun; Baker, A. G.; Adelson, Harriet G.

doi:10.1007/bf01207736

Cited by 12 publications

(8 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Decreased successful pregnancy outcomes in advanced age are suggested to be caused by decreased blood flow to the endometrium, thus limiting the access to various hormones (10). Similarly, different studies showed that the age of recipients over 45 years negatively affects pregnancy outcomes (11)(12)(13). Contrary to these studies, many stated that the age of recipients in OD does not affect pregnancy outcomes, which is similar to this study (5,(14)(15)(16)(17).…”

Section: Discussionsupporting

confidence: 77%

The pivotal role of the number of transferred embryos in oocyte donation cycles: A retrospective cohort study

ÖNAL¹,

Güngör²,

Gürbüz³

et al. 2022

J. Exp. Clin. Med.

View full text Add to dashboard Cite

This research aimed to show the role of the number of transferred embryos on pregnancy outcomes of the oocyte donation cycles (ODC). This retrospective cohort study included 122 ODCs performed at a private in vitro fertilization (IVF) center between 2020 June - 2021 January. Cases with severe male infertility, tuboperitoneal, and endometrial factors were not included in the study. The median (interquartile range) recipient age was 43 (30–54) years. ODC results revealed that 10.7% of the cases were negative, 4.9% were biochemical pregnancies, and 84.4% were clinical pregnancies. Pregnancy outcomes were checked; miscarriage, preterm, and term delivery rates were 5.7%, 3.9%, and 90.4%, respectively. The rate of recipients for the younger than 40 years was 32%, between the 40–44 years was 27%, and between 45–54 years was 41% respectively. Statistically significant difference was not observed between age groups in terms of endometrial thickness (p = 0.059), number of transferred embryos (p = 0.857), number of ODC attempt (p = 0.666), live birth rate (p = 0.1), and other pregnancy outcomes (p > 0.05, for all). A total of 96 (78.7%) embryo transfers (ET) resulted in a live birth. In 8.2% (n=10) of cases, single embryo transfer (SET) and in 91.8% (n=112) of cases, double embryo transfer (DET) was performed. The number of embryos transferred was statistically significantly higher among cases that resulted in live births compared to cases without live births (p = 0.002). Significant difference was not found in terms of the recipient age (p = 0.392), male age (p = 0.108), endometrial thickness (p = 0.478), and the number of attempt (p = 0.777) between cases resulted in live birth or not. The only parameter that affects the live birth rates in ODC is the number of transferred embryos.

show abstract

Section: Discussionsupporting

confidence: 77%

The pivotal role of the number of transferred embryos in oocyte donation cycles: A retrospective cohort study

ÖNAL¹,

Güngör²,

Gürbüz³

et al. 2022

J. Exp. Clin. Med.

View full text Add to dashboard Cite

show abstract

“…Although there was no significant association between endometrial thickness and implantation, pregnancy outcome was improved in patients showing an endometrial lining thickness >8 mm. There have been controversial reports in this regard (31)(32)(33)(34)(35). We were unable to find a correlation between the ultrasonographic appearance of the endometrium (pattern) and pregnancy or implantation rates (32,35).…”

Section: Discussionmentioning

confidence: 72%

Untitled

Mirkin

Gimeno

Bovea

et al. 2003

Journal of Assisted Reproduction and Genetics

View full text Add to dashboard Cite

Although no single or combined donor or recipient variable(s) could be identified as predictor(s) of pregnancy, the data suggest that donors < or = 33 years of age with basal cycle day 3 serum levels of FSH 4-8 IU/L, LH < 8 IU/L, and E2 < 70 pg/mL had an optimal outcome. Transfer of two selected embryos on day 3 yields a favorable pregnancy outcome while significantly decreasing the occurrence of multiple pregnancies. These policies, in addition to embryo cryopreservation, were associated with optimal pregnancy outcome in oocyte donation.

show abstract

“…Although the effect of increased maternal age on reproduction has been widely studied, the influence of the oocyte donor's age on the recipient's pregnancy success is still controversial. While many investigators have reported that recipient age is inversely related to oocyte donation success (Levran et al, 1991;Check et al, 1993;Meldrum, 1993;Borini et al, 1996;Marcus et al, 2016), others have not observed this relationship (Abdalla et al, 1997;Paulson et al, 1997;Remohi et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

Predictive factors for successful pregnancy in an egg-sharing donation program

Braga¹,

Setti²,

Iaconelli³

et al. 2020

JBRA Assisted Reproduction

View full text Add to dashboard Cite

Objective: To investigate the predictive factors for successful pregnancy in oocyte recipient ICSI cycles in an egg-sharing donation program.Methods: Analysed data were obtained via chart review of 1505 vitrified oocytes donated from 268 patients to 225 oocyte recipients, undergoing 307 ICSI cycles. Patients were participating in an egg-sharing donation program between January 2015 and May 2017. Adjusted generalised linear models were used to investigate the impact of oocyte donor and recipient characteristics on recipients' pregnancy achievement.Results: Implantation rate in the oocyte donor was highly correlated with pregnancy achievement in the oocyte recipient's cycles (ExpB: 1.181, CI: 1.138-1.226, p<0.001). The ROC curve analysis demonstrated that the implantation rate in the oocyte donor has a strong predictive value for pregnancy success in the oocyte recipient (area under the curve: 0.98, CI: 0.95-0.99, p<0.001).

show abstract

The effect of the age of the recipients on pregnancy rates following donor-oocyte replacement

Cited by 12 publications

References 17 publications

The pivotal role of the number of transferred embryos in oocyte donation cycles: A retrospective cohort study

The pivotal role of the number of transferred embryos in oocyte donation cycles: A retrospective cohort study

Untitled

Predictive factors for successful pregnancy in an egg-sharing donation program

Contact Info

Product

Resources

About