The effect of surfactants modification on nanocrystalline cellulose for paclitaxel loading and release study

Putro, Jindrayani Nyoo; Ismadji, Suryadi; Gunarto, Chintya; Yuliana, Maria; Santoso, Shella Permatasari; Soetaredjo, Felycia Edi; Ju, Yi

doi:10.1016/j.molliq.2019.03.037

Cited by 32 publications

(33 citation statements)

References 31 publications

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“…10). The detail of the procedure can be seen elsewhere 34 . Relatively high cell viability (up to 83%, after 24 h incubation; and ~79%, after 36 h incubation) was maintained by using 25 μg/mL of MIL-100(Fe) which shows biocompatibility of this material, at this concentration 35 .…”

Section: Resultsmentioning

confidence: 99%

Hydrothermal Synthesize of HF-Free MIL-100(Fe) for Isoniazid-Drug Delivery

Simon

Anggraeni

Soetaredjo

et al. 2019

Sci Rep

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101

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Sustainable development of drug delivery materials with good biocompatibility and controlled-release is a popular topic among researchers. In this research study, we demonstrated the potential of the metal-organic framework, that is MIL-100(Fe), as a drug delivery platform for isoniazid (INH). The MIL-100(Fe) was prepared by using the hydrofluoric acid-free hydrothermal method. Several physical measurements were conducted to characterize the MIL-100(Fe), including x-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen sorption, and thermal-gravimetric (TG). The synthesized MIL-100(Fe) has octahedron-shaped particles with superior properties, that is large surface area (1456.10 m2/g) and pore volume (1.25 cm3/g). The drug loading rate and capacity were determined by means of adsorption kinetic and isotherm. The studied INH@MIL-100(Fe) adsorption system kinetics follow the pseudo-first-order model, while the isotherm system follows the Langmuir model with the maximum adsorption capacity of 128.5 mg/g at 30 °C. MIL-100(Fe) shows adequate biocompatibility, also exhibits a reasonable and controlled drug release kinetics. The results obtained show that MIL-100 (Fe) can be a good choice of drug delivery platform among other available platforms.

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Section: Resultsmentioning

confidence: 99%

Hydrothermal Synthesize of HF-Free MIL-100(Fe) for Isoniazid-Drug Delivery

Simon

Anggraeni

Soetaredjo

et al. 2019

Sci Rep

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101

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“…These functional groups supported the bindings of the hydrophilic drug onto modified CNCs. As described in Table 5 , various investigations of CNCs modifications have been done and applied for many hydrophobic drugs, such as paclitaxel [ 66 , 72 ], docetaxel, etoposide [ 66 ], luteolin, luteoloside [ 69 ], curcumin [ 70 , 73 , 74 ], and tosufloxacin tosylate [ 65 ].…”

Section: Cellulose Nanocrystals (Cncs)mentioning

confidence: 99%

A Review of Lignocellulosic-Derived Nanoparticles for Drug Delivery Applications: Lignin Nanoparticles, Xylan Nanoparticles, and Cellulose Nanocrystals

2021

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Due to their biocompatibility, biodegradability, and non-toxicity, lignocellulosic-derived nanoparticles are very potential materials for drug carriers in drug delivery applications. There are three main lignocellulosic-derived nanoparticles discussed in this review. First, lignin nanoparticles (LNPs) are an amphiphilic nanoparticle which has versatile interactions toward hydrophilic or hydrophobic drugs. The synthesis methods of LNPs play an important role in this amphiphilic characteristic. Second, xylan nanoparticles (XNPs) are a hemicellulose-derived nanoparticle, where additional pretreatment is needed to obtain a high purity xylan before the synthesis of XNPs. This process is quite long and challenging, but XNPs have a lot of potential as a drug carrier due to their stronger interactions with various drugs. Third, cellulose nanocrystals (CNCs) are a widely exploited nanoparticle, especially in drug delivery applications. CNCs have low cytotoxicity, therefore they are suitable for use as a drug carrier. The research possibilities for these three nanoparticles are still wide and there is potential in drug delivery applications, especially for enhancing their characteristics with further surface modifications adjusted to the drugs.

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“…The crystalline property of NC indicates by the appearance of the diffraction peak at 2θ of 15.5 and 22.6°, which corresponds to the lattice plane (110) and (200), respectively. [10][11] The crystallinity index (CI, %) of the NC can be calculated by employing the Segal equation: 12 ( ) 200 110 CI % 100% 200…”

Section: Characterization Of Ncmentioning

confidence: 99%

“…The obtained CI was comparable to that of reported literature, i.e., within the range of 52.7 to 99.2%. [10][11]13 The FTIR spectra of the NC is summarized in Table 1; the FTIR of NC reported in other literature was also provided for comparison purposes. It was observed that the FTIR spectra of the NC sample are comparable with the different reported spectra.…”

Section: Characterization Of Ncmentioning

confidence: 99%

“…It was observed that the FTIR spectra of the NC sample are comparable with the different reported spectra. 11,[14][15] Specifically, the characteristic band corresponding to the -OH group stretching is observed at a wavenumber of 3300 cm -1 . The bands observed at 2898, 1645, 1400, and 1052 conform to the C-H stretching, -OH bending/C = O stretching, C-H bending, and C-O/C-C stretching, respectively.…”

Section: Characterization Of Ncmentioning

confidence: 99%

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Utilization of Nanocrystalline Cellulose for Adsorption of Divalent Cobalt Ions in the Aqueous Phase

Santoso

Angkawijaya

Kurniawan

et al. 2020

Fine Chemical Engineering

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Nanocrystalline cellulose (NC) is a cellulose derivative product that has attracted a lot of attention because of its versatile applications, one of which is in adsorption. In this study, NC was prepared through H2SO4-hydrolysis of filter paper. Several physical characterizations were employed to confirm the formation of the NC nanoparticles, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) analysis, and Fourier transform infrared spectroscopy (FTIR). The nano-rod-shaped NC particles, with an average particle length of 255 nm, were observed from the electron micrographs. The resemblance characteristic of NC with cellulose was demonstrated from the occurrence of XRD peaks at (110) and (200) lattice plane. The FTIR bands’ spectra of the NC are similar to that of the reported literature. The NC was utilized as the adsorbent for the removal of cobalt ions in the synthetic solution. The effect of pH on the removal of cobalt ions by NC was evaluated by employing potentiometric titration. It was revealed that the complexation between the two compounds occurs greater at a pH of 6.6. The adsorption isotherm of cobalt ions was investigated at three different temperatures of 30, 45, and 60°C. The adsorption isotherm was found to be well fitted with the Langmuir model, with the maximum adsorption capacity of 47.53 mg g-1 at 30°C. The adsorption capacity was found to decline as the temperature increased, where the maximum adsorption capacity was 44.62 ± 2.32 and 40.56 ± 2.03 mg g-1 at 45 and 60°C, respectively. The adsorption of cobalt ions on NC shows the exothermic adsorption behavior.

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The effect of surfactants modification on nanocrystalline cellulose for paclitaxel loading and release study

Cited by 32 publications

References 31 publications

Hydrothermal Synthesize of HF-Free MIL-100(Fe) for Isoniazid-Drug Delivery

Hydrothermal Synthesize of HF-Free MIL-100(Fe) for Isoniazid-Drug Delivery

A Review of Lignocellulosic-Derived Nanoparticles for Drug Delivery Applications: Lignin Nanoparticles, Xylan Nanoparticles, and Cellulose Nanocrystals

Utilization of Nanocrystalline Cellulose for Adsorption of Divalent Cobalt Ions in the Aqueous Phase

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