The effect of supervised exercise therapy for intermittent claudication on lower limb lean mass

Vun, Simon; Miller, Michelle; Delaney, Christopher; Allan, Richard B.; Spark, J.I.

doi:10.1016/j.jvs.2016.06.099

Cited by 12 publications

(11 citation statements)

References 30 publications

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“…The influence of such training on the nutritional status of patients with IC has been poorly addressed in the literature. This is despite the potential consequences associated with increasing metabolic demands through high-intensity exercise without the concurrent administration of adequate nutrition in this already nutritionally vulnerable group [45,46]. In fact, evidence exists to suggest that combined nutrition and exercise interventions in the rehabilitation setting are preferable, with those receiving exercise alone demonstrating greater declines in nutritional status and physical health [47,48,49].…”

Section: Nutrition In the Management Of Peripheral Arterial Diseasementioning

confidence: 99%

Nutritional Considerations for Peripheral Arterial Disease: A Narrative Review

2019

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Those with peripheral arterial disease (PAD) require important considerations with respect to food and nutrition, owing to advanced age, poor diet behaviours and immobility associated with the disease process and co-morbid state. These considerations, coupled with the economic effectiveness of medical nutrition therapy, mandate that dietetic care plays a vital role in the management of PAD. Despite this, optimising dietetic care in PAD remains poorly understood. This narrative review considers the role of medical nutrition therapy in every stage of the PAD process, ranging from the onset and initiation of disease to well established and advanced disease. In each case, the potential benefits of traditional and novel medical nutrition therapy are discussed.

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Section: Nutrition In the Management Of Peripheral Arterial Diseasementioning

confidence: 99%

Nutritional Considerations for Peripheral Arterial Disease: A Narrative Review

2019

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“…Several studies have even suggested a potentially detrimental effect of attaining the pain threshold. 148 Furthermore, the results of studies investigating exercise training using a submaximal pain threshold seem to be comparable with those of studies involving attainment of the pain threshold. 149e152…”

Section: What Is Not Consensual?mentioning

confidence: 73%

The Role of Teamworking in Error Reduction during Vascular Procedures

Soane¹,

Bicknell²,

Mason³

et al. 2014

Annals of Vascular Surgery

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“…However, it should be noted that structured walking exercise alone, as suggested for patients with LEAD [39,40], has little or no effect on muscle loss prevention, while clinically meaningful gains in muscle mass can be achieved by progressive resistance training [41]. In a study conducted by Vun et al, a loss of lean mass of the thighs of the symptomatic as well as asymptomatic leg, after the completion of a standard, treadmill-based, supervised exercise in LEAD patients, was observed [43]. This finding is consistent with the results found in a randomized controlled study where patients lost strength in both limbs after changing from strength to treadmill training [44].…”

Section: Discussionmentioning

confidence: 99%

Lower Lean Mass Is Associated with Greater Arterial Stiffness in Patients with Lower Extremity Artery Disease

Muster

Gütl

Pregartner

et al. 2021

JPM

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Background: Arterial stiffness is independently associated with lower extremity artery disease (LEAD). Although obesity is already known as an independent cardiovascular risk factor, it was found that, paradoxically, in patients diagnosed with cardiovascular disease, an increase in body mass index (BMI) was associated with a decrease in mortality. However, the underlying mechanism of this paradoxical association remain uncertain. In this study, we firstly hypothesize that arterial stiffness correlates with body mass; secondly, the underlying mechanism of the association for patients with LEAD is individual body composition, in particular, lean mass. Methods: The present study was performed as a single-center, prospective, observational analysis. A total of 412 patients with current or previously diagnosed LEAD (Rutherford Classification 2–4) were included, the cfPWV and AIx were measured as indices of arterial stiffness, and a body composition assessment was performed. Results: In male patients, there was a significantly negative correlation between the AIx and lean mass coefficient (p = 0.004, 95% CI: −0.28 (−0.48–0.09)). Conclusion: For patients with peripheral arterial disease, our data show that lower lean mass in male patients is associated with increased arterial stiffness as measured by the AIx. Therefore, progressive resistance training may be beneficial for the reduction in arterial stiffness in PAD patients in secondary prevention.

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The effect of supervised exercise therapy for intermittent claudication on lower limb lean mass

Cited by 12 publications

References 30 publications

Nutritional Considerations for Peripheral Arterial Disease: A Narrative Review

Nutritional Considerations for Peripheral Arterial Disease: A Narrative Review

The Role of Teamworking in Error Reduction during Vascular Procedures

Lower Lean Mass Is Associated with Greater Arterial Stiffness in Patients with Lower Extremity Artery Disease

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