The Effect of Storage on the Vitamin B6 Content of a Packaged Army Ration, with a Note on the Human Requirement for the Vitamin

Harding, Richard S.; Plough, Irvin C.; Friedemann, Theodore E.

doi:10.1093/jn/68.2.323

Cited by 30 publications

(4 citation statements)

References 8 publications

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“…The Health Council of the Netherlands () set an Estimated Average Requirement (EAR) based on studies on vitamin B6 status assessed by plasma PLP concentrations, the tryptophan load test and α‐EAST in men (Harding et al., ; Baker et al., ; Yess et al., ; Miller and Linkswiler, ; Canham et al., ; Park and Linkswiler, ; Miller et al., ) and in women (Donald et al., ; Shin and Linkswiler, ; Brown et al., ; Driskell et al., ; Kretsch et al., ; Hansen et al., , , ; Huang et al., ). The Council considered a coefficient of variation (CV) of 20% for setting the Recommended Dietary Allowances (RDAs), due to uncertainty about the variation in the requirement (Hansen et al., ).…”

Section: Overview Of Dietary Reference Values and Recommendationsmentioning

confidence: 99%

Dietary Reference Values for vitamin B6

2016

EFS2

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Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derives Dietary Reference Values (DRVs) for vitamin B6. The Panel considers that plasma pyridoxal 5 0 -phosphate (PLP) concentration is the biomarker of status suitable for deriving DRVs for vitamin B6. Considering that a plasma PLP concentration of 30 nmol/L, as a population mean, is indicative of an adequate vitamin B6 status, the Panel proposes to use this cut-off value to set Average Requirements (ARs). Population Reference Intakes (PRIs) are derived for adults and children from ARs, assuming a coefficient of variation (CV) of 10%. For women, the AR and PRI are set at 1.3 and 1.6 mg/day. For men, the AR of 1.5 mg/day is derived by an allometric scaling from the AR for women, and a PRI of 1.7 mg/day is set. For all infants aged 7-11 months, an Adequate Intake of 0.3 mg/day is set, averaging the results of two extrapolation approaches based on an allometric scaling: upwards extrapolation from the estimated vitamin B6 intake of exclusively breastfed infants from birth to 6 months, and downwards extrapolation from the ARs for adults applying a growth factor. For all children, ARs are derived from adult ARs using an allometric scaling and growth factors. For children of both sexes aged 1-14 years, ARs range between 0.5 and 1.2 mg/day. For children aged 15-17 years, the Panel derives the same ARs as for adults. PRIs for children aged 1-17 years range between 0.6 and 1.7 mg/day. Extrapolation of ARs by an allometric scaling considered differences in reference body weight. For pregnant and lactating women, additional requirements are considered, based on the uptake of vitamin B6 by the fetal and maternal tissues and the losses through breast milk, and PRIs of 1.8 and 1.7 mg/day, respectively, are derived.

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Section: Overview Of Dietary Reference Values and Recommendationsmentioning

confidence: 99%

Dietary Reference Values for vitamin B6

2016

EFS2

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“…The reaction of the aldehyde group of pyridoxal (PL) or pyridoxal phosphate (PLP) with proteins during food processing has been shown to account for at least a portion of the losses of vitamin B6 reported in proteinaceous foods as a result of thermal processing or storage (Register et al 1950;Tomarelli et al 1955;Harding et al 1959). As previously discussed, interaction of PL or PLP with protein sulfhydryl groups has been reported to yield bis-4-pyridoxyl disulfide as a product Wendt and Bernhart 1960); however, the reductive bonding of these B6 compounds to amino groups which yields pyridoxyl amino compounds such as pyridoxyllsine appears to be a more quantitatively significant reaction Kirk 1977, 1978A;Gregory and Ink, unpublished).…”

Section: Binding Of Vitamin B6 Aldehydes To Food Proteinsmentioning

confidence: 99%

Chemical Changes of Vitamins during Food Processing

Gregory¹

1985

Chemical Changes in Food During Processing

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“…This may be evi dence for great sensitivity of this test. On the other hand, the use of a relatively large dose of tryptophan, particularly if the diet already con tains a high level of protein, may represent an unrealistic demand on the vitamin B G activity of the tissues (84), and lead to an erroneously high estimate of requirements.…”

Section: Vitamin Bmentioning

confidence: 99%