The effect of size and age on depuration rates of diarrhetic shellfish toxins (DST) in mussels (Mytilus edulis L.)

Duinker, Arne; Bergslien, M.; Strand, Øivind; Olseng, Christine Daae; Svardal, Asbjørn

doi:10.1016/j.hal.2006.10.003

Cited by 31 publications

(27 citation statements)

References 28 publications

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“…2). Inverse relationships between weight-specific toxin concentrations and body size have been previously reported during laboratory and field exposure of bivalves to DA, PSTs and DSTs (Novaczek et al, 1992;Moroño et al, 2001;Duinker et al, 2007). In contrast, Roelke et al (1993) found no relationship between body weight and DA concentration in C. virginica, although only low toxin concentrations (1-2 gg −1 ) were attained by oysters in their laboratory study.…”

Section: Effect Of Body Size On Da Uptake and Eliminationmentioning

confidence: 69%

“…Contrary to oysters, however, mussels exhibited a significant (1.4-1.7-fold) gain in body mass over the 14-d depuration period. In some cases, differential growth can explain most of the differences in toxin elimination by bivalves, as reported in a long-term (73 d) field study in which DST elimination was greater in faster-growing, smaller M. edulis than in larger individuals [(SL = 28 and 46 mm, respectively (Duinker et al, 2007)]. This is caused by dilution of toxin content due to body mass gain, as also reported for PSTs in M. edulis and S. solidissima (Bricelj et al, 1990;Bricelj and Cembella, 1995) and for DA in crabs Cancer magister (Lund et al, 1997).…”

Section: Inter-specific Differences In Da Uptake and Eliminationmentioning

confidence: 86%

“…1 and 3 for the uptake and depuration phases respectively. faster growth of smaller individuals must also be considered in some other cases (Bricelj and Cembella, 1995;Duinker et al, 2007), as discussed above.…”

Section: Effect Of Body Size On Da Uptake and Eliminationmentioning

confidence: 99%

“…For diarrhetic shellfish toxins (DSTs) and PSTs, toxin uptake and elimination rates are inversely related to body size, although dilution effects by differential growth must be considered mainly in species or stages that exhibit slow toxin loss and/or fast growth rates (Bricelj and Shumway, 1998;Moroño et al, 2001;Duinker et al, 2007). The influence of bivalve body size on DA uptake and elimination, however, remains controversial.…”

Section: Introductionmentioning

confidence: 99%

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Domoic acid uptake and elimination kinetics in oysters and mussels in relation to body size and anatomical distribution of toxin

2010

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Section: Effect Of Body Size On Da Uptake and Eliminationmentioning

confidence: 69%

Section: Inter-specific Differences In Da Uptake and Eliminationmentioning

confidence: 86%

Section: Effect Of Body Size On Da Uptake and Eliminationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Domoic acid uptake and elimination kinetics in oysters and mussels in relation to body size and anatomical distribution of toxin

2010

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“…Un protocole expérimental est conçu pour décrire les cinétiques durant 3 semaines d'expérience et comparer les taux de détoxication d'une part chez des moules nourries et d'autre part chez des moules maintenues à jeun. Ce protocole est appliqué sur des moules prélevées au même endroit, à la même saison, en 2006et 2007. L'acide okadaïque, principale toxine diarrhéique produite par la micro-algue responsable de la toxicité (Dinophysis acuminata) est suivi au cours de la décontamination par l'analyse des extraits de glande digestive hydrolysés (OA total) et nonhydrolysés (OA libre) ; ceci afin d'estimer les concentrations en acyl-esters (7-O-acyl-esters de l'acide okadaïque).…”

Section: Introductionunclassified

Effect of food supply on the detoxification in the blue mussel,Mytilus edulis, contaminated by diarrhetic shellfish toxins

Marcaillou

Haure

Mondeguer

et al. 2010

Aquat. Living Resour.

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-The objective of this study was to identify a possible effect of food on the acceleration of decontamination in blue mussels, Mytilus edulis, containing diarrhetic toxins belonging to the okadaic acid (OA) structural group. An experimental protocol was designed to describe and compare the decontamination kinetics and detoxification rates of naturally OA-contaminated mussels that had either received or not received food for three weeks. The protocol was applied in two trials (in June 2006 and June 2007, called Ker06 and Ker07), conducted one year apart on samples of mussels collected in the same area, at the same season. Okadaic acid (OA), the main lipophilic toxin produced by the toxic alga Dinophysis acuminata, was analysed over the course of the decontamination, in hydrolysed (total OA) and non hydrolysed (free OA) digestive gland extracts, in order to estimate acyl-esters (7-O-acyl-ester derivatives of OA) concentrations. OA analyses were also made for toxin presence in biodeposits and in the aqueous phase. Bivalve physiological status was evaluated by biomass measurements (dry weight of flesh) and two biochemical compounds (total lipid and glycogen concentrations). Measured physiological parameters showed that mussels did not suffer under experimental conditions. Both trials showed that the food accelerated the elimination of free and total OA. This effect cannot be attributed to a dilution of the toxin in the tissue, as results expressed in toxin burden led to the same conclusion. The kinetic models of decontamination differed between the two experiments: the model was linear for Ker06, provided that the values corresponding to the first two days were discarded, whereas data fitted a decreasing exponential curve better in Ker07. Detoxification rates increased as the food supply increased. After three weeks of experimentation, the detoxification rates for total OA in Ker06 and Ker07 were 52 and 61%, respectively, in unfed mussels and 90 and 89% in fed mussels (with the highest level in Ker07). Comparisons between the free OA and esters showed that detoxification rate was higher for free OA than for esters, whatever the level of food supply. The results of this study suggest that food increase probably accelerates elimination of OA and OA-esters but the latter are eliminated at a lower speed. Key words:Mussel / Feeding / Digestive gland / Depuration / Okadaic acid / Acyl esters / Marine lipophilic biotoxins / Mass spectrometry Résumé -L'objectif de cette étude est de mettre en évidence un effet éventuel de la nourriture sur la vitesse de décontamination de moules, Mytilus edulis, contenant des toxines diarrhéiques de la famille de l'acide okadaïque (OA). Un protocole expérimental est conçu pour décrire les cinétiques durant 3 semaines d'expérience et comparer les taux de détoxication d'une part chez des moules nourries et d'autre part chez des moules maintenues à jeun. Ce protocole est appliqué sur des moules prélevées au même endroit, à la même saison, en 2006et 2007. L'acide okadaïque, principale ...

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Mussels and Public Health

2021

Marine Mussels

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The effect of size and age on depuration rates of diarrhetic shellfish toxins (DST) in mussels (Mytilus edulis L.)

Cited by 31 publications

References 28 publications

Domoic acid uptake and elimination kinetics in oysters and mussels in relation to body size and anatomical distribution of toxin

Domoic acid uptake and elimination kinetics in oysters and mussels in relation to body size and anatomical distribution of toxin

Effect of food supply on the detoxification in the blue mussel,Mytilus edulis, contaminated by diarrhetic shellfish toxins

Mussels and Public Health

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