Abstract:ObjectivesThe present trial aimed to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles.MethodsIn this double blind, randomized and placebo-controlled trial, sixty eligible postmenopausal women were randomly assigned into the fennel and placebo groups. Total blood cholesterol, cholesterol fractions, and triglycerides were tested at the baseline, and after three-month follow-up.ResultsThere was no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-densi… Show more
“…Comparison of two groups did not show any significant difference in total cholesterol ( P = 0.103), LDL-C ( P = 0.104) and HDL-C levels ( P = 0.266), triglyceride ( P = 0.679) between the two groups. 24 …”
ObjectivesThe aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females.MethodsA search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare, and menopause.ResultsFennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram. The comparison of these two groups regarding the mean bone mineral density and bone mineral content (P = 0.14, P = 0.504); the total hip femoral (P = 0.42, P = 0.66); the trochanter (P = 0.075, P = 0.07); the intertrochanter (P = 0.84, P = 0.93); and the femoral neck (P = 0.43, P = 0.64) did not show any significant statistical differences; however, a statistically significant difference regarding the vasomotor symptoms (P < 0.01) was found. The other significant differences are related to the values of the total cholesterol (P = 0.103); low-density lipoprotein cholesterol, or LDL-C (P = 0.104); high-density lipoprotein cholesterol, or HDL-C (P = 0.266); triglyceride (P = 0.679); body weight (P = 0.212); body mass index (P = 0.041); waist and hip circumferences (P = 0.365); and fat distribution (P = 0.337) between the two groups. The standardized mean difference (SMD) values of sexual activity (SMD = 0.638; P < 0.001), and maturation value (SMD = 0.601; P = 0.003) are highly significant among the fennel-treated women compared with the placebo group.ConclusionsAccording to the findings of the present study, fennel is important in the relieving of vasomotor symptoms, vaginal itching, dryness, dyspareunia, sexual function, sexual satisfaction, and sleep distribution.
“…Comparison of two groups did not show any significant difference in total cholesterol ( P = 0.103), LDL-C ( P = 0.104) and HDL-C levels ( P = 0.266), triglyceride ( P = 0.679) between the two groups. 24 …”
ObjectivesThe aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females.MethodsA search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare, and menopause.ResultsFennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram. The comparison of these two groups regarding the mean bone mineral density and bone mineral content (P = 0.14, P = 0.504); the total hip femoral (P = 0.42, P = 0.66); the trochanter (P = 0.075, P = 0.07); the intertrochanter (P = 0.84, P = 0.93); and the femoral neck (P = 0.43, P = 0.64) did not show any significant statistical differences; however, a statistically significant difference regarding the vasomotor symptoms (P < 0.01) was found. The other significant differences are related to the values of the total cholesterol (P = 0.103); low-density lipoprotein cholesterol, or LDL-C (P = 0.104); high-density lipoprotein cholesterol, or HDL-C (P = 0.266); triglyceride (P = 0.679); body weight (P = 0.212); body mass index (P = 0.041); waist and hip circumferences (P = 0.365); and fat distribution (P = 0.337) between the two groups. The standardized mean difference (SMD) values of sexual activity (SMD = 0.638; P < 0.001), and maturation value (SMD = 0.601; P = 0.003) are highly significant among the fennel-treated women compared with the placebo group.ConclusionsAccording to the findings of the present study, fennel is important in the relieving of vasomotor symptoms, vaginal itching, dryness, dyspareunia, sexual function, sexual satisfaction, and sleep distribution.
“…Foeniculum vulgare Mill commonly called fennel has been used in traditional medicine and contains fatty acids, phenolic components, hydrocarbons and volatile components. Afiat et al (2018) assesses the effects of fennel (Foeniculum vulgare Mill.) on lipid profiles in postmenopausal women.…”
Hyperlipidemia is associated with elevated cholesterol and triglyceride levels which is a risk factor for atherosclerosis. Spices being an integral part of culinary culture around the world are known to possess anti-cholesterol compounds and increase the high density lipoprotein cholesterol. This review presents a comprehensive scientific data on the anticholesterol/hypolipidemic activities of various spices used in traditional medicine and cuisine. Bioactive compounds from spices with anti-hyperlipidemic activities and their mode of action are summarized. The findings reaffirm the importance of spices by suggesting their anti-hyperlipdemic/anti-cholesterol activities to prevent cardiovascular diseases.
“…Afiat et al en mujeres postmenopáusicas, después de 12 semanas de tratamiento, encontraron un aumento del 4.72% de c-HDL en el grupo experimental al cual se le administró cápsulas de hinojo 3 veces al día 21 . En contraste con este estudio, en los resultados obtenidos de c-HDL en el grupo experimental se encontró una reducción del 13,4%, por lo que se recomienda prolongar el tiempo de su consumo para comprobar este efecto.…”
RESUMENIntroducción: Foeniculum vulgare (hinojo) es una hierba proveniente de la familia Apiaceae. Su cultivo y uso en la medicina tradicional es amplio en el Perú. Objetivo: Demostrar el efecto del Foeniculum vulgare en el perfil lipídico de adultos jóvenes con sobrepeso y obesidad. Materiales y Métodos: Se realizó un estudio de tipo experimental puro prospectivo. Participaron 34 adultos jóvenes, formándose dos grupos de 17 participantes cada uno; un grupo control (GC), a los que se les administró un té placebo de gelatina neutra y uno experimental (GE), a los que se les dio té de hinojo (250 ml), ambos durante 21 días. Resultados: Se aplicó la prueba t-Student (p<0,05) y la prueba Wilcoxon para muestras relacionados y la U de Mann-Whitney para muestras independientes al evaluar triglicéridos. Después de tres semanas de administración de Foeniculum vulgare en el GE el colesterol y triglicéridos bajó significativamente, 5,49% y 26,36%, respectivamente (p<0,05). Conclusión: El consumo del Foeniculum vulgare en adultos jóvenes con sobrepeso y obesidad reduce significativamente los niveles de triglicéridos y colesterol total; no hubo variación significativa de los niveles de c-LDL ni c-HDL.
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