2023
DOI: 10.1016/j.jdiacomp.2023.108436
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The effect of SGLT2 inhibitors, GLP1 agonists, and their sequential combination on cardiometabolic parameters: A randomized, prospective, intervention study

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Cited by 15 publications
(12 citation statements)
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“…It was observed that systemic vascular resistance and lipoprotein(a) levels improved to a greater extent with liraglutide than empagliflozin, along with improvement in BMI, body and visceral fat, blood pressure, and HbA1c. However, no improvement in arterial stiffness indices was observed with empagliflozin or liraglutide or their combination in this study [ 115 ].…”
Section: Emerging Pharmacotherapiesmentioning
confidence: 77%
“…It was observed that systemic vascular resistance and lipoprotein(a) levels improved to a greater extent with liraglutide than empagliflozin, along with improvement in BMI, body and visceral fat, blood pressure, and HbA1c. However, no improvement in arterial stiffness indices was observed with empagliflozin or liraglutide or their combination in this study [ 115 ].…”
Section: Emerging Pharmacotherapiesmentioning
confidence: 77%
“…In line with our results, Bechlioulis et al found no effect of combination treatment or any of the treatments alone on cf-PWV. 20 The study was open-label, and patients were at lower CV risk compared with our population.…”
Section: Discussionmentioning
confidence: 94%
“…Some studies found no effect of SGLT2is on arterial stiffness, 20,34,35 including a recent meta‐analysis, 36 while others observed a reduction 19,37 . Similarly, studies of GLP‐1RAs have found reduced arterial stiffness post‐treatment, 19,31,38–40 whereas other studies did not find an effect 20,41 . Differences in study design, populations enrolled, and adjustment for BP may account for some of these differences.…”
Section: Discussionmentioning
confidence: 99%
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