The Effect of Pulmonary Ischaemia on Lung Function

Hw, Hankinson; Fr, Edwards

doi:10.1136/thx.14.2.122

Cited by 17 publications

(2 citation statements)

References 1 publication

(1 reference statement)

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“…Blades et al (1952Blades et al ( , 1953 and Blades (1954) concluded that 30 minutes' complete bronchial and pulmonary arterial occlusion was the safe limit. Hankinson and Edwards (1959) and Lewis et al (1961) found that up to one hour was permissible, and pulmonary oedema occurred after two hours' total ischaemia.…”

Section: Discussionmentioning

confidence: 98%

“…As long ago as 1856, Virchow studied the effects of pulmonary ischaemia. More recent work has been reported by Blades (1954) and by Blades, Beattie, Hill, and Thistlethwaite (1952), Blades, Pierpont, Samadi, and Hill (1953), Hankinson and Edwards (1959), and Lewis, Demos, Connaughton, and Poticha (1961). These 523 experiments were done with temporary total ischaemia.…”

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confidence: 81%

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Pulmonary circulatory arrest.

Williams¹,

Manley²,

Drew³

1965

Thorax

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Section: Discussionmentioning

confidence: 98%

mentioning

confidence: 81%

Pulmonary circulatory arrest.

Williams¹,

Manley²,

Drew³

1965

Thorax

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Hypoxia of the Lung Parenchyma During Cardiopulmonary Bypass

Almond¹,

Jones²,

Snyder³

et al. 1966

Arch Surg

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An evaluation of the tolerance of the autotransplanted canine lung against warm ischemia

Yamazaki

Wada

Aoki

et al. 1989

The Japanese Journal of Surgery

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Left lung autotransplantation was performed in mongrel dogs to examine the limitation of tolerance of the deflated lung against warm ischemia in a warm ischemic time (WIT) range of 60-360 minutes. The animals were divided into the 4 following groups according to the duration of WIT and the use of heparin: Group 1; WIT 60-120 min., heparin (-), Group 2; WIT 120-240 min., heparin (+), Group 3; WIT 240-360 min., heparin (+), and Group 4; WIT 240-360 min., heparin (-). All the Group 1 animals tolerated a right pulmonary artery ligation on the 6th postoperative day, but some of the Group 2 animals died immediately after the reimplantation due to pulmonary edema. All the Groups 3 and 4 animals died. The PaO2 values during the right pulmonary artery occlusion, immediately after the reimplantation, correlated well with the survival of the animals. The maximum tolerable WIT of the deflated dog lung was considered to be 120 minutes.

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The Effect of Pulmonary Ischaemia on Lung Function

Cited by 17 publications

References 1 publication

Pulmonary circulatory arrest.

Pulmonary circulatory arrest.

Hypoxia of the Lung Parenchyma During Cardiopulmonary Bypass

An evaluation of the tolerance of the autotransplanted canine lung against warm ischemia

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