Abstract:In this paper, the effects of systemic pentoxifylline administration on normal and diabetic wound healing are studied. Twenty-four normoglycemic and 24 diabetic rats were compared, exploring the healing of standardized (15×15 mm) full-thickness wounds by secondary intention. Twelve rats of both groups received intraperitoneal pentoxifylline 10 mg/kg per day. The strength of the healed tissues was evaluated by straining tests, the healing time of each wound was recorded, and the healed tissues were examined his… Show more
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