The Effect of Mesobotox Together with Intense Pulsed Light on Facial Wrinkles and Erythema

Abstract

Facial ageing is a gradual process which could be due to intrinsic and extrinsic causes, it ultimately results in the appearance of gravity-induced tissue ptosis, wrinkles, epidermal and dermal atrophy, dryness, senile lentigo, flushing, telangiectasia, and enlarged pores. Mesobotox treatment is a technique of microinjections of diluted Botulinum toxin type A (BTX) to preserve the facial mobility in order to preserve the natural beauty. BTX treatment enhances the aesthetic improvements attained with IPL. Ten patients of age ranging between 40 - 60 years old ( mean 45±10.3 years) with skin type ranging between (III - V) were treated using BTX and Intense Pulsed Light (IPL) using cutoff filter 550 nm with a fluence of 25 J/cm<sup>2</sup> together as a combination therapy. All patients received standard IPL treatment and were assigned to receive eight 0.1 mL intradermal injections of BTX in each cheek (8 U total dose). Vertical lines within the forehead also received five 0.1 mL intradermal injections of BTX. Small wrinkles and fine lines, erythema, apparent pore size, skin texture, and overall appearance were evaluated after one week. A significantly higher proportion of patients showed improvement in small wrinkles and erythema with IPL plus BTX compared with the baseline demonstrated by computerized image analysis. In conclusion, A combined therapy of mesobotx and IPL is an effective and safe treatment for fine wrinkles, telangiectasia, flushing

Microbotox for the treatment of wide facial pores: A promising therapeutic approach

“…Botulinum toxin locally blocks the parasympathetic response on erector pili muscle and the sebaceous glands, and consequently, leading to an overall increase in the sympathetic response that exerts an increased force on the arector pili muscle, leading to contracture of the muscle and a decrease in the size of the pores. 5,6 Microbotox treatment is a simple, nonsurgical treatment with low risks and no downtime. It shows numerous therapeutic benefits for the patients as it shrinks large/prominent facial pores, reduces facial oil production, lessens the risk of acne and rosacea, improves the skin texture, and tightens the skin of the face.…”

“…Erector pili muscle works through the sympathetic/ parasympathetic enervation. Botulinum toxin locally blocks the parasympathetic response on erector pili muscle and the sebaceous glands, and consequently, leading to an overall increase in the sympathetic response that exerts an increased force on the arector pili muscle, leading to contracture of the muscle and a decrease in the size of the pores 5,6 …”

“…Complete muscle paralysis is achieved by injecting 2‐4 Botox units (0.05‐ 0.1 mL) to target muscles. It was noticed that Botox injection has an aesthetic bonus by giving the smooth lustrous appearance of the facial skin due to decreased sweat and sebaceous gland 5,6 . Microbotox, also called mesobotox, is the injection of multiple microdroplets of diluted Botulinum toxin A into the upper dermis.…”

“…It was noticed that Botox injection has an aesthetic bonus by giving the smooth lustrous appearance of the facial skin due to decreased sweat and sebaceous gland. 5,6 Microbotox, also called mesobotox, is the injection of multiple microdroplets of diluted Botulinum toxin A into the upper dermis. It is used clinically to improve the tone, the texture of the skin, as well as decreasing flushing, enlarged pores, and seborrhea.…”

“…It is used clinically to improve the tone, the texture of the skin, as well as decreasing flushing, enlarged pores, and seborrhea. 6,7 The aim of the present study was to evaluate the efficacy and safety of microbotox in treatment of wide facial pores.…”