The Effect of Maternal Drinking before Conception and in Early Pregnancy on Infant Birthweight

Passaro, Kristi Tolo; Little, Ruth E.; Savitz, David A.; Noss, John

doi:10.1097/00001648-199607000-00007

Cited by 85 publications

(58 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No effect was seen in infants born to women who drank weekly in early pregnancy, less than weekly or not at all (Passaro et al, 1996). Shu et al (1995) found that alcohol consumption in the first trimester (average four drinks per week) was associated with a 155 g reduction in fetal weight, even after adjustment for number of cigarettes smoked.…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Alcohol drinking and risk of small for gestational age birth

et al. 2006

View full text Add to dashboard Cite

Objective: To assess if alcohol drinking is a risk factor for small for gestational age (SGA) birth. Methods: Case-control study. Cases were 555 women (mean age 31 years, range 16-43) who delivered SGA babies at the Clinica Luigi Mangiagalli and the Obstetric and Gynecology Clinic of the University of Verona. The controls were 1966 women (mean age 31 years, range 14-43) who gave birth at term (X37 weeks of gestation) to healthy infants of normal weight at the hospitals where cases had been identified. Results: No increase in the risk of SGA birth was observed in women drinking one or two drinks/day in pregnancy, but three or more per day increased the risk: odds ratios (OR) were 3.2 (1.7-6.2) for X3 drinks during the first trimester, 2.7 (1.4-5.3) during the second and 2.9 (1.5-5.7) during the third. Conclusions: The study shows an increased risk of SGA births in mothers who drink X3 units/day of alcohol in pregnancy.

show abstract

Section: Discussionmentioning

confidence: 98%

“…However, despite its clinical significance, the effect of moderate alcohol drinking in pregnancy on the risk of small for gestational age (SGA) birth is controversial (Day et al, 1989;Shu et al, 1995;Windham et al, 1995;Passaro et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

Alcohol drinking and risk of small for gestational age birth

et al. 2006

View full text Add to dashboard Cite

show abstract

“…The potential negative effect of alcohol drinking in pregnancy on birth weight and preterm delivery is controversial (Die et al, 1989;Shu et al, 1995;Windham et al, 1995;Passaro et al, 1996;Makarechian et al, 1998). For example, a recent cohort study based on postal questionnaires conducted in Denmark (Kesmodel et al, 2000) has suggested that heavy alcohol drinking during the first 30 weeks of gestation increases the risk of preterm births about three-fold.…”

Section: Introductionmentioning

confidence: 99%

Moderate alcohol drinking and risk of preterm birth

et al. 2003

View full text Add to dashboard Cite

Objective: We have analysed the association between alcohol drinking before and during the three trimesters of pregnancy and risk of preterm birth of babies with normal weight for gestational age or with low weight for gestational age (SGA). Design: Case-control study. Setting: General and university hospitals in Italy. Subjects: Cases were 502 women who delivered preterm births o37 weeks gestation. The controls included 1966 women who gave birth at term (Z37 weeks of gestation) to healthy infants of normal weight (ie between 10th and 90th centile according to the Italian standard) on randomly selected days at the hospitals where cases had been identified. Interventions: Interview. Results: No increased risk of preterm birth was observed in women drinking one or two drinks/die in pregnancy, but three or more drinks/die increased the risk (multivariate odds ratios (OR) 2.0 for Z3 drinks during the first trimester, 1.8 during the second and 1.9 during the third). When the analysis was conducted separately for preterm births with normal weight or SGA, the increased risk was observed in preterm SGA only (multivariate OR for Z3 drinks/die during the first trimester ¼ 3.6, 95% confidence interval (CI) 1.3-11.1); the estimated multivariate OR for Z3 drinks/die during the first trimester of preterm babies with normal weight for gestational age was only slightly above unity and not statistically significant (multivariate OR 1.4, 95% CI 0.5-3.7). Conclusions: The study shows an increased risk in mothers who drink Z3 die units alcohol in pregnancy of preterm births. Sponsorship: Ministero della Ricerca Scientifica.

show abstract

“…In the interpretation of the existing epidemiological studies regarding the harmful effects of binge drinking, our conclusion regarding the decline in the accuracy of the reported information on binge drinking as the recall period increases is important. The major part of the existing studies has collected information on binge drinking in the second half of pregnancy or subsequent to birth (Tolo and Little, 1993;Olsen, 1994;Pascoe et al, 1995;Passaro et al, 1996;Iyasu et al, 2002;Whitehead and Lipscomb, 2003) and therefore the information on binge drinking is most likely underestimated. Due to this underestimation, actual exposed women may be categorized as non-exposed and the estimates could probably be biased towards the null-value.…”

Section: Discussionmentioning

confidence: 99%

“…If such periods exist, it may explain why previous studies have failed to find any association between binge drinking and birth weight, length at birth, head circumference, gestational age, Apgar score and malformations. (Tolo and Little, 1993;Olsen and Tuntiseranee, 1995;Passaro et al, 1996;Kesmodel, 2001;Whitehead and Lipscomb, 2003).…”

Section: Introductionmentioning

confidence: 99%

Do women give the same information on binge drinking during pregnancy when asked repeatedly?

et al. 2006

View full text Add to dashboard Cite

Objective: To study if pregnant women give the same answers to questions on frequency and timing of binge drinking when asked more than once during and after pregnancy. Design: Cohort study. Setting: The Danish National Birth Cohort. Subjects: The study is based on 76 307 pregnant women with repeated information on binge drinking during the early part of pregnancy and 8933 pregnant women with information on binge drinking during pregnancy weeks 30-36, obtained while pregnant and 6 months after delivery. Results: More women reported binge drinking, if the interview took place close to the period in question. As the report of binge drinking was highest in the first of two interviews referring to the same period, as well as women who participated in the first interview in pregnancy week 12 or earlier reported more binge drinking compared to women who participated in the interview later in pregnancy. Conclusions: Self-reported information on binge drinking is more frequently under-reported when the recall period is long. To improve the validity of data on binge drinking, future birth cohorts should obtain information several times during pregnancy.

show abstract

The Effect of Maternal Drinking before Conception and in Early Pregnancy on Infant Birthweight

Cited by 85 publications

References 27 publications

Alcohol drinking and risk of small for gestational age birth

Alcohol drinking and risk of small for gestational age birth

Moderate alcohol drinking and risk of preterm birth

Do women give the same information on binge drinking during pregnancy when asked repeatedly?

Contact Info

Product

Resources

About