The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction

Ekmekçi, Perihan Elif; Bengisun, Züleyha Kazak; Akan, Burak; Kazbek, Baturay Kansu; Ozkan, Kemal Sefa; Süer, A. H.

doi:10.1007/s00167-012-2093-4

Cited by 30 publications

(30 citation statements)

References 19 publications

(22 reference statements)

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“…Numerous studies in the orthopaedic and anesthesia literature have looked at their efficacy compared with other modalities of postoperative pain management. 12,13,21,26,27,32 Advantages of FNB cited by these studies include lower visual analog scale (VAS) scores for pain at rest and with movement during the immediate postoperative period. 10,15,28 Other studies have shown no significant difference in pain control, side effects, opioid consumption, and readiness for discharge between FNB and local infiltration anesthesia or multimodal anesthesia.…”

Section: -In-5mentioning

confidence: 99%

Femoral Nerve Block Is Associated With Persistent Strength Deficits at 6 Months After Anterior Cruciate Ligament Reconstruction in Pediatric and Adolescent Patients

et al. 2014

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Section: -In-5mentioning

confidence: 99%

Femoral Nerve Block Is Associated With Persistent Strength Deficits at 6 Months After Anterior Cruciate Ligament Reconstruction in Pediatric and Adolescent Patients

et al. 2014

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“…It was shown to be effective as a postoperative analgesic in orthopedic surgery (7,8). The analgesic property of magnesium is associated with inhibition of the N-methyl-D-aspartate (NMDA) receptor and modulation of calcium channels (9). Furthermore, its addition to local anesthetics prolongs anesthesia duration and maximizes their effects (10,11).…”

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confidence: 99%

Efficacy of intra-articular magnesium for postoperative analgesia in total hip arthroplasty

Wen

et al. 2017

Biomedical Reports

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Abstract. The aim of the present study was to compare the efficacy of intra-articular magnesium sulphate and a saline placebo for postoperative pain control following total hip arthroplasty (THA). Sixty patients underwent THA and were randomly allocated into two groups to receive intra-articular injections of either 10 ml magnesium sulphate (100 mg/ml; magnesium group, n=30) or 10 ml normal saline solution (control group, n=30). Postoperative analgesia was maintained by intravenous morphine injection. The outcome measurements were visual analogue score (VAS), morphine consumption and Harris hip score (HHS). The two groups were well matched. The outcome of VAS at rest was significantly lower at postoperative hours 6 and 12 in the magnesium group as compared with the control group, although the difference was insignificant preoperatively and at postoperative hours 2, 4, 24 and 48, and days 3, 7 and 14. This indicator during activity was also lower in the magnesium group at postoperative hour 24 than that of the control group, although the difference was insignificant preoperatively and at hour 48, and days 7 and 14. The consumption of morphine (the total quantity) at 0-6, 6-12 and 0-48 h in the magnesium group was significantly lower than in the control group, although no significant differences were observed at 12-24 and 24-48 h between the groups. The improvements of HHS from preoperative to postoperative scores were statistically significant, however, no significant differences were identified between groups. Thus, the findings indicate that intra-articular magnesium sulphate injections provided improved pain control and reduced the need for morphine when compared with a saline placebo following THA.

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“…A study by Ekmekci et al (13) showed that addition of magnesium to levobupivacaine prolongs the sensory and motor block duration without increasing side effects, enhances the quality of postoperative analgesia and increases patient satisfaction; however, the addition of magnesium delays the time to first mobilisation and decreases rescue analgesic requirements. Our study shows similar effect in prolongation of post-operative analgesia without increase in adverse effects.…”

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confidence: 99%

Ultrasound Guided Supraclavicular Brachial Plexus Block With and Without Magnesium Sulphate: A Comparative Study

Yangtse¹,

Shanmugavelu²,

Jeyabaskaran³

2016

jemds

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The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction

Cited by 30 publications

References 19 publications

Femoral Nerve Block Is Associated With Persistent Strength Deficits at 6 Months After Anterior Cruciate Ligament Reconstruction in Pediatric and Adolescent Patients

Femoral Nerve Block Is Associated With Persistent Strength Deficits at 6 Months After Anterior Cruciate Ligament Reconstruction in Pediatric and Adolescent Patients

Efficacy of intra-articular magnesium for postoperative analgesia in total hip arthroplasty

Ultrasound Guided Supraclavicular Brachial Plexus Block With and Without Magnesium Sulphate: A Comparative Study

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