The effect of lavandula essential oils on release of niflumic acid from collagen hydrolysates

Ghica, Mihaela Violeta; Albu, Mădălina Georgiana; Kaya, Durmuş; Popa, Lăcrămioara; Öztürk, Şevket; Rusu, Laura-Cristina; Dinu-Pîrvu, Cristina-Elena; Chelaru, Ciprian; Albu, Luminita; Meghea, Aurelia; Nițipir, Cornelia

doi:10.1007/s11814-015-0284-7

Cited by 13 publications

(12 citation statements)

References 18 publications

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“…used as an antiseptic [8][9][10][11][12][13]. High correlation figures obtained comparing with the paraffin histopathological results support the conclusion that methylene blue staining test is a reliable test for assessing disease free resection margins.…”

Section: Experimental Partmentioning

confidence: 64%

Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Hainăroşie¹,

Zainea²,

Hainăroşie³

et al. 2018

Rev. Chim.

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Lingual squamous cell carcinoma is one of the most frequent localization of the oral carcinomas. The tongue neoplasia represents nearly 40% of the oral carcinomas. Recent studies showed an increasing trend of lingual carcinoma in young patients. Several staining tests have been described to early detect the disease. After detection, disease free margins resection will increase the survival rate. This study aims to analyze the methylene blue staining test in achieving disease free resection margins in lingual squamous cell carcinoma.

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Section: Experimental Partmentioning

confidence: 64%

Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Hainăroşie¹,

Zainea²,

Hainăroşie³

et al. 2018

Rev. Chim.

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“…The methylene blue staining test is already method for assessing the resection margins when a tumoral pathology is concerned, although it has so far been used when malignancies were concerned [10]. Another advantage when using this substance is the fact that it helps in the scaring process and it has a local bacteriostatic and antioxidant effect [11][12][13].…”

Section: Resultsmentioning

confidence: 99%

Methylene blue staining test in assessing safe margins in laryngeal papillomatosis

Hainăroşie¹,

Pițuru²,

Stefanescu³

et al. 2017

Rev. Chim.

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Laryngeal papillomatosis, although a viral and benign disease, poses a great challenge for the ENT surgeon from a therapeutical point of view. The lack of a curative treatment and the tendency of the papillomatosis to recur in an extensive manner require an aggressive treatment. Although multiple medical therapies are available, their results are not always the desired ones. That is why nowadays the focus of the therapy is on the surgical approach. The best results may be obtained thru multiple surgeries, with resection of all papilloma foci. Although this approach may impact the quality of life of the patients due to the multiple interventions required, the overall result translates into a physiologic airway. Because the site where the lesions first appear is at an epithelial level, tendency to use methods of early diagnosis, that make the disease recognizable before extensive lesions, is the natural tendency. Also, it is extremely important to remove all papilloma lesions during surgery, thus minimizing the chances of recurrence or at least increasing the interval between interventions.The aim of this paper is to present the methylene blue staining test as an adjuvant method of evaluating the resection margins during surgery for laryngeal papillomatosis. This method can improve the results of surgery and increase the patient�s adherence to treatment, by decreasing the number of interventions required.

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“…These compounds contribute to the total antioxidant defense system of the human body and help to minimize the oxidative stress in the cells [139][140][141][142][143]. In addition to that, the EOs of Lavandula have a great antioxidant capacity since they generally include thymol, linalool, limonene, fenchone, camphor, camphene, β-caryophyllene, 1,8-cineol and trans-α-necrodyl acetate [110,113,114,137]. An interesting study about the application of UV-B doses during plant growth in the promotion of biomass in L.  intermedia showed that this method increased the accumulation of phenolic compounds although with less antioxidant capacity [144].…”

Section: Antioxidant Activity Of Lavandula Spp Plantsmentioning

confidence: 99%

Plants of the GenusLavandula: From Farm to Pharmacy

Salehi

Mnayer

Özçelik

et al. 2018

Natural Product Communications

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The Lavandula genus, belonging to the Lamiaceae, includes 39 species, with nearly 400 registered cultivars. Lavandula are worldwide plants that occur over the Mediterranean, Europe, North Africa, southwest Asia to southeast India. Lavandula plants have been used since ancient time to flavor and preserved food, to treat diseases including wound healing, sedative, antispasmodic, microbial and viral infections. Numerous researches have described the chemical composition and the primary components of lavender oils are the monoterpenoids (linalool, linalyl acetate, 1,8-cineole, β-ocimene, terpinen-4-ol, and camphor), sesquiterpenoids (β-caryophyllene and nerolidol) and other terpenoid compounds (e.g., perillyl alcohol). The high concentrations of linalyl acetate make them attractive in perfumery, flavoring, cosmetics and soap industries. Currently, data on the antimicrobial activity of lavender plants have been scientifically confirmed. Indeed, lavender essential oils possess wide spectra of biological activities such as antispasmodic, carminative, analgesic, sedative, hypotensive, antiseptic, antimicrobial, antifungal, antidiuretic and general tonic action. In addition, clinical studies support their uses as treatment of health conditions. However, further clinical studies are necessary to define the magnitude of the efficacy, mechanisms of action, optimal doses, long-term safety, and, potential side effects of lavender plants.

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The effect of lavandula essential oils on release of niflumic acid from collagen hydrolysates

Cited by 13 publications

References 18 publications

Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Methylene blue staining test in assessing safe margins in laryngeal papillomatosis

Plants of the GenusLavandula: From Farm to Pharmacy

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