Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Hainăroşie, Răzvan; Zainea, Viorel; Hainăroşie, Mura; Pietroşanu, Cătălina; Ioniţă, Irina; Pițuru, Silviu; Stefanescu, Dragos Cristian

doi:10.37358/rc.17.12.5998

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…If one does not identify the lesion, the use of staples should be avoided and a circumferential resection under the direct guidance of the endoscopist is recommended to avoid the rupture of the tumor with subsequent spillage. In four cases, we used the preoperative marking of the lesion with methylene blue, but the endoscopist had to pay close attention to the depth of the gastric layers and the quantity when administering the substance, since it can always dissipate in a large area of the gastric wall (27,28). This makes it difficult for the surgeon to correctly resect the area where the tumor is located.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience

Slavu¹,

Aleçu²,

Tulin³

et al. 2019

JMMS

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Introduction. Gastrointestinal stromal tumors (GISTs) represent a rare type of gastrointestinal neoplasms. Resection with negative margins has been established as a mainstay treatment, but laparoscopic resections are still open to debate. Material and method. This retrospective study was conducted at a single institution, with data collected over 2 years (01.01.2017-01.01.2019). The variables examined were age, tumor location with regard to the gastric wall, the results of the intraoperative endoscopy, intraoperative and postoperative complications, the surgical technique, and histopathological reports. Results. We identified 12 relevant cases, of which 8 were females and 4 males. The average tumor diameter was 2.3 cm. The majority of the lesions were located on the anterior gastric wall (8 cases), on the small curvature (2 cases), and in the pyloric region (2 cases). Intraoperative endoscopy was performed successfully in 10 cases in order to identify the lesions and guide the resection. The average operative time was 120 minutes and the average hospital stay was 5 days. The gastric wall with the lesion was resected using an Ultrasonic device, a 2-cm oncological safety margin was preserved. Conclusion. Complete surgical resection independent from the tumor size represents the current optimal treatment. From a surgical point of view, these tumors must be considered malignant and the surgeon must respect principles of oncological surgery. Maintaining tumor integrity at dissection is critical for the patient's long-term prognosis. Laparoscopic resection independent of the tumor size is feasible.

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Section: Discussionmentioning

confidence: 99%

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience

Slavu¹,

Aleçu²,

Tulin³

et al. 2019

JMMS

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“…Keywords: dacryocystitis, methylene blue, lacrimal sac, dacryocystectomy MB was synthesised for the first time in 1876 by Heinrich Caro at Badishe Anilin and Sado Fabrik (BASF), being used in textile dyeing [1][2][3], then 15 years later it was the first antiseptic introduced in clinical cure of malaria [1]. MB is now used in a large variety of dyes for multiple purposes and in medicine for a number of therapeutic and diagnostic procedures [2,[4][5][6][7][8][9][10].…”

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confidence: 99%

Intraoperative Identification of Lacrimal Sac by Means of Methylene Blue

Bogdănici¹,

Costea²,

Dimitriu³

et al. 2018

Rev. Chim.

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Methylene blue (MB) has many uses in medicine, being applied as a treatment for infections, malaria, methemoglobinemia, as a dye for diagnosis and for staining of cells, tissues and bacteria. In elderly patients with associated high anaesthetic risk, dacryocystectomy is an alternative to dacryocystorhinostomy. This is an observational clinical study for two cases of chronic dacryocystitis where dacryocystectomy combined with MB (1%) staining of lacrimal sac was performed. Case no.1 - an 81-year old female patient with arterial hypertension, atherosclerosis, pulmonary fibrosis, and lower limb varices complainted of recurrent epiphora, muco-purulent secretions in both eyes, inflammatory oedema of the left perisacular region for the past 6 months. Case no. 2 - a 74-year old female patient with hypothyroidism suffered from chronic epiphora in the left eye with a purple-red oedema of the inferior eyelid and perisacular region. Symptoms reoccurred in the last 10 months despite topical and systemic therapy with antibiotics and anti-inflamatory drugs. Dacryocystectomy was performed under local anaesthesia in both patients. MB (1%) was used to irrigate the lacrimal sac in order to facilitate its localisation, dissection and excision. Results: Case no.1. Ectopic lacrimal sac. Case no.2. Enlarged lacrimal sac (7.5/14 mm). The histopathological examination revealed a trachomatous dacryocystitis, respectively a chronic non-suppurative non-granulomatous dacryocystitis. Their postoperative evolution was without complications, except for a mild epiphora. In conclusion, dacryocystectomy appears to be a less traumatising alternative to dacryocystorhinostomy. The staining of the lacrimal sac with MB (1%) in dacryocystectomy facilitates its identification and dissection, especially when it is ectopic.

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Methylene Blue Test in Assessing Disease Free Margins in Lingual Carcinoma Resection

Cited by 2 publications

References 8 publications

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience

Intraoperative Identification of Lacrimal Sac by Means of Methylene Blue

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