“…Mecobalamin accelerates transmethylation in nerve tissues and increases biolytic synthesis of nucleic acids and phospholipids [12,13]. Its efficacy in experimental studies has been documented with regard to the regeneration of peripheral nerves that previously showed Wallerian degeneration [14], regeneration in acrylamid neuropathy [15], uremic neuropathy [16], segmental demyelination due to diabetic peripheral neuropathy [17], and axonal degeneration due to adriamycin neuropathy [18]. In clinical studies, the efficacy of mecobalamin has been reported in nerverelated diseases such as peripheral neuropathy associated with diabetic polyneuropathy [19,20].…”