The effect of increasing honey concentration on the properties of the honey/polyvinyl alcohol/chitosan nanofibers

Sarhan, Wessam A.; Azzazy, Hassan M. E.; El‐Sherbiny, Ibrahim M.

doi:10.1016/j.msec.2016.05.006

Cited by 58 publications

(27 citation statements)

References 51 publications

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“…Samples of 100% honey were highly viscous and difficult to manipulate [23], therefore the 75% w/v concentration was selected to investigate the effects of the different honey types on the bacterial growth at different time points. The time points selected were every hour for the first 5 hrs, 24 and 25 hrs.…”

Section: Resultsmentioning

confidence: 99%

The Antibacterial Activity of Libyan Honey against Gram Negative Bacilli: Potential Treatment Agent for Infectious Diseases?

Elmarbet

Shaban

Doro

et al. 2018

JAMMR

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Aims: Honey has is a rich source of many compounds that exhibit anti-microbial, anti-inflammatory and pro-angiogenic properties. The emergence of antibiotic resistance in a wide variety of bacterial pathogens has generated renewed interest in natural antimicrobials. The aim of the present study Elmarbet et al.; JAMMR, 25(7): 1-10, 2018; Article no.JAMMR.39349 2 was to assess the antibacterial activity of Libyan honey in vitro. Methodology: The antibacterial activities of selected Libyan origin honey including Libyan Spring, AL-Sader, Thyme and Al-Hanone (at 25%, 50%, 75% and 100 % (w/v)) were tested against Yersinia enterocolitica, Escherichia coli and Proteus mirabilis using agar well-diffusion assay. The measurement of exponential bacterial growth curves was used to determine the effects on the microbial growth pattern spectrophotometrically at 600 nm. In addition, plate count methods were used to enumerate the effects of honey on the viable bacterial count. Results and Discussion: Honey progressively inhibited bacterial growth at higher concentrations. This effect was variable depending on the honey type. For example, Al Sader honey showed the highest inhibition zones 21.3 mm 0.8 against P. mirabilis followed by Thyme (21 mm 0.5) and spring (20 mm 0.5). Al-Hanone honey only exhibited effects against E. coli (14 mm 0.5 and 8 mm 0.4 at 100% w/v and 75% w/v, respectively). The Al Sader, spring and Thyme honey significantly reduced the Yersinia enterocolitica bacteria growth curve (p<0.05). All tested honey significant reduced E. coli growth from 5hrs compared to the control samples (p<0.05). Conclusion: All honey tested showed inhibition of bacterial growth. Concentrated honeys were more effective against Yersinia enterocolitica, Escherichia coli and Proteus mirabilis. The efficacy of different types of honey was dependent on the honey concentration and origin. Original Research Article

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Section: Resultsmentioning

confidence: 99%

The Antibacterial Activity of Libyan Honey against Gram Negative Bacilli: Potential Treatment Agent for Infectious Diseases?

Elmarbet

Shaban

Doro

et al. 2018

JAMMR

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“…Recently, Sarhan et al [68] reported the use of an automatic analyzer called mercury porosimetry to measure the size of the pores; however, it only measures sizes in the range of 0.0018-400 μm, finding that in chitosan nanofibers/honey/PVA the diameter of the pores is 140 μm.…”

Section: Porosity and Pore Distributionmentioning

confidence: 99%

Overview of Electrospinned Chitosan Nanofiber Composites for Wound Dressings

Vega-Cázarez¹,

Sánchez‐Machado²,

JaimeLópez-Cervantes³

2018

Chitin-Chitosan - Myriad Functionalities in Science and Technology

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Chitosan has a medical application because of its natural origin and properties of biodegradability, biocompatibility, nontoxicity, and antimicrobial capacity. Electrospinning produces non-woven nanofibers to wound dressing with high specific surface area and small pores. These properties are favorable for absorption of exudates and prevent the penetration of bacteria, thus promoting wound healing. For this reason, chitosan blends are used to produce nanofiber dressings, and the characterization of the structural, mechanical, and biological properties is very promising for further studies. Nowadays, the researchers are seeking for biomaterials that provide modern dressings with many qualities, which are designed to promote wound healing. In this chapter, the electrospinning parameters that affect the nanofiber properties based on chitosan to prepare wound dressings are highlighted.

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“…Also, the crystal structure of amoxicillin can improve the antimicrobial effect and the stability of the drug, prolong the action duration of the drug and slow down the dissolution of the drug [10]. Sarhan et al [11], investigated the effect of increasing honey concentration to polyvinyl alcohol/chitosan nanofibers combined with different concentration of honey for determining the effect of different concentration of honey on the properties of besides, antibacterial study and swelling degree verified the successful combination of honey in nanofibers. Due to antibacterial properties and high cross-linked network, they concluded the process parameters have improved some properties of nanofibers to compatible their applications in wound healing/dressing.…”

Section: Introductionmentioning

confidence: 99%

“…The Contagion of wound surfaces often causes retarded wound healing or increases the hazard of septicemia, which fatality is the main cause of woundassociated death. The swelling degree of samples has an important role in the antibacterial activity and wound restoration due to solvent-holding capacity which can absorb predict exudates by swelling and help a quick restoration of wounds [11]. The recent analysis, study the combination of chitosan, polyvinylalcohol and sodium alginate for determining the effect of swelling behavior on these physical characteristics and developing the antibacterial activity to use in several biomedical applications like wound healing.…”

Section: Introductionmentioning

confidence: 99%

Microbial activity and swelling behavior of chitosan/polyvinyl alcohol/sodium alginate semi-natural terpolymer interface containing amoxicillin for wound dressing applications

2019

Biointerface Res Appl Chem

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Samples of equimass fraction chitosan/polyvinyl alcohol/sodium alginate semi-natural terpolymer with and without gradient concentration of amoxicillin, a topical antibiotic drug were prepared via traditional casting techniques. Changing in antibacterial activity and swelling degree have been assessed using the zone of inhibition method and pH sensitivity study. Upon increasing the amoxicillin concentration, the enhancement of antibacterial activity was performed against (2g) positive bacteria (S. aureus, B. subtilis), (2g) negative bacteria (E. coli, P. aeuroginosa) and fungus (C. albicans). Increasing the concentration of amoxicillin caused a decreasing in the swelling ratio (SR) at neutral (pH= 7) and basic medium (pH= 8, 9) due to increase cross-linked and rigidity of the network. Hence the results strongly support the possibility of using this novel Cs/PVA/SA with different amounts of amoxicillin to compatible used in tissue regeneration and antimicrobial applications.

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The effect of increasing honey concentration on the properties of the honey/polyvinyl alcohol/chitosan nanofibers

Cited by 58 publications

References 51 publications

The Antibacterial Activity of Libyan Honey against Gram Negative Bacilli: Potential Treatment Agent for Infectious Diseases?

The Antibacterial Activity of Libyan Honey against Gram Negative Bacilli: Potential Treatment Agent for Infectious Diseases?

Overview of Electrospinned Chitosan Nanofiber Composites for Wound Dressings

Microbial activity and swelling behavior of chitosan/polyvinyl alcohol/sodium alginate semi-natural terpolymer interface containing amoxicillin for wound dressing applications

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