The Effect of Hydroxychloroquine Treatment on Blood Sugar Level, Serum Lipid Profile and the Retina in Systemic Lupus Erythematosus Patients

Sarhan, Rania M.; Shaban, A. R.; Hamid, Mohamed; Salem, Heba F.

doi:10.5455/medscience.2015.04.8334

Cited by 1 publication

(1 citation statement)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The etiology of SLE is still unknown. It can influence any organ in the body, particularly the skin, joints, kidneys and cardiovascular system [2]. Cardiovascular manifestations are common in SLE patients, which may have a wide range of severity [3].…”

Section: Introductionmentioning

confidence: 99%

Study of Cardiovascular Diseases Risk in Systemic Lupus Erythematosus Can Be Comparable with Type 2 Diabetes Mellitus

Abdalla

Elsawy

Alshafi

et al. 2021

JAMMR

View full text Add to dashboard Cite

Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Cardiovascular manifestations are common in SLE, which may have a wide range of severity and one of the major causes of morbidity and mortality. Diabetes mellitus (DM) is one of the most common metabolic diseases. One of the major risk factor for cardiovascular diseases is DM, which is the most common cause of death among diabetic patients. Aim of the Work: evaluation of subclinical atherosclerosis as a predictor for CVD in patients with SLE and DM. Methods: 50 SLE patients, 50 T2DM patients, 50 diabetic SLE patients and 50 healthy controlled subjects were enrolled in this study. They were undergone to Doppler examination of the extra-cranial portion of the carotid and femoral arteries measuring the intima-media thickness. Result: In SLE the subclinical atherosclerosis was present in 22% of patients and was significantly associated with older age (p˂0,001), high blood pressure (p=0,023), overweight (p=0,004), proteinuria (p˂0,001), total cholesterol (p=0,004), active disease (p=0,007), high SLEDAI score (p˂0,001) and long duration of SLE (p˂0,001); whereas in diabetic patients the subclinical atherosclerosis was documented in 24% and was significantly associated with older age (p˂0,001), overweight (p˂0,001), proteinuria (p˂0,001), low hemoglobin (p=0,041), total cholesterol (p=0,001), LDL (p˂0,001), uncontrolled diabetes (p=0,005) and long duration of diabetes (p=0,001) but in SLE diabetic patients the subclinical atherosclerosis was documented in 44% of patients. Conclusion: Subclinical atherosclerosis is frequent in patients with SLE and increases with increased disease activity. Subclinical atherosclerosis in SLE diabetic patients was significantly more than that in SLE or diabetic patients.

show abstract

Section: Introductionmentioning

confidence: 99%

Study of Cardiovascular Diseases Risk in Systemic Lupus Erythematosus Can Be Comparable with Type 2 Diabetes Mellitus

Abdalla

Elsawy

Alshafi

et al. 2021

JAMMR

View full text Add to dashboard Cite

show abstract

The Effect of Hydroxychloroquine Treatment on Blood Sugar Level, Serum Lipid Profile and the Retina in Systemic Lupus Erythematosus Patients

Abstract: The aim of this study was to evaluate the effect of hydroxychloroquine (HCQ)

Cited by 1 publication

References 38 publications

Study of Cardiovascular Diseases Risk in Systemic Lupus Erythematosus Can Be Comparable with Type 2 Diabetes Mellitus

Study of Cardiovascular Diseases Risk in Systemic Lupus Erythematosus Can Be Comparable with Type 2 Diabetes Mellitus

Contact Info

Product

Resources

About