2021
DOI: 10.1007/s10787-021-00881-0
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The effect of glutamine supplementation on serum levels of some inflammatory factors, oxidative stress, and appetite in COVID-19 patients: a case–control study

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Cited by 21 publications
(23 citation statements)
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“…Glutamate negatively correlates with the pro-inflammatory cytokines IL-6 and IL-18 but positively correlates with (especially CD4 + ) T cells [ 44 , 63 , 95 ]. Of note, nutritional glutamine supplementation caused a decrease of IL-1β, TNF-α and high-sensitivity C-reactive protein (hs-CRP), in COVID-19 patient sera, compared to the non-supplemented control group [ 103 ]. These finding establish the role of glutamine depletion in the pathogenesis of COVID-19.…”
Section: Mechanistic Biomarkers Of Covid-19mentioning
confidence: 99%
“…Glutamate negatively correlates with the pro-inflammatory cytokines IL-6 and IL-18 but positively correlates with (especially CD4 + ) T cells [ 44 , 63 , 95 ]. Of note, nutritional glutamine supplementation caused a decrease of IL-1β, TNF-α and high-sensitivity C-reactive protein (hs-CRP), in COVID-19 patient sera, compared to the non-supplemented control group [ 103 ]. These finding establish the role of glutamine depletion in the pathogenesis of COVID-19.…”
Section: Mechanistic Biomarkers Of Covid-19mentioning
confidence: 99%
“…Among the nutrients that affect immune function, vitamin D, magnesium, vitamin B 12 , and vitamin C have been reported to significantly reduce the proportion of severely ill patients and prolong survival [13,[16][17][18][19]. Although immuneboosting nutrients, such as glutamine, selenium, and zinc, reportedly have antiviral effects [13,20,21], appropriate supply levels, methods, types, and administration periods have yet to be established. European Society for Clinical Nutrition and Metabolism guidelines suggest providing the recommended daily amounts of vitamins and trace elements [8].…”
Section: Comparison With Previous Studiesmentioning
confidence: 99%
“… 53 Mohajeri et al found in a case‐controlled study that glutamine supplementation in Covid‐19 reduced the level of proinflammatory cytokines and associated complications. 54 …”
Section: The Link Between Covid‐19 and MMmentioning
confidence: 99%
“…53 Mohajeri et al found in a case-controlled study that glutamine supplementation in Covid-19 reduced the level of proinflammatory cytokines and associated complications. 54 Notably, expression of angiogenic factors, HIF-1, and glutamine deficiency could link Covid-19 severity and MM in the pathogenesis of cardiovascular complications.…”
Section: Cardiovascular Complicationsmentioning
confidence: 99%
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