The effect of glucocorticosteroid administration on fetal movements and biophysical profile scores in normal pregnancies

Jackson, J; Kleeman, Steven D.; Doerzbacher, Meg; Lambers, Donna S.

doi:10.1080/jmf.13.1.50.53

Cited by 26 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Administration of corticosteroids (betamethasone and dexamethasone) for enhancement of fetal lung maturity is also reported to reduce FM and the fetal heart rate (FHR) variability detected by CTG over the 2 days following administration (10,23,24). To assess whether the decrease in FMs was directly related to corticosteroid use, Jackson et al (24) studied a low‐risk ambulatory population. They found that corticosteroid use was associated with decreased FM by subjective maternal assessment and objective biophysical profile scores.…”

Section: Factors Which Influence the Fm Patternmentioning

confidence: 99%

“…Fetal breathing was the biophysical component affected in their study. Decreased fetal breathing results in decreased fetal lung fluid exhalation, which is seen as a reduction in the amniotic fluid index, possibly resulting in decreased FM (24). The pathophysiology of corticosteroid changes in FM and FHR variability is still unclear and has not been definitely proven (10,13,19,24).…”

Section: Factors Which Influence the Fm Patternmentioning

confidence: 99%

See 1 more Smart Citation

Decreased fetal movements: background, assessment, and clinical management

Olesen

Svare

2004

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

A reduction or cessation of fetal movements (FMs) is frequently reported by pregnant women and causes concern and anxiety. However, the clinical significance of a history of reduced FMs remains unclear, and the assessment and management of these pregnancies is controversial. This article is a review of the literature on decreased FMs found in medline and the cochrane library using the search phrases: decreased FMs, perinatal outcome, FM monitoring, and fetal assessment. Formal counting of FMs by the pregnant woman could possibly identify the fetuses, which are at risk of compromise, thus allowing for appropriate action. However, the benefit of this intervention has not been definitely proven. Cardiotocography, umbilical/uterine artery Doppler velocimetry, and ultrasonography have been used for antepartum fetal assessment in pregnancies with decreased FMs, but the evidence of a clinical benefit is limited. The effects of fetal assessment with vibroacoustic stimulation and biophysical profile are unknown and should be further evaluated. Present recommendations on the management of pregnancies with decreased FMs are based on limited and inconsistent scientific evidence. There is a need for further well-designed studies in order to provide evidence-based guidelines in the future.

show abstract

Section: Factors Which Influence the Fm Patternmentioning

confidence: 99%

Section: Factors Which Influence the Fm Patternmentioning

confidence: 99%

Decreased fetal movements: background, assessment, and clinical management

Olesen

Svare

2004

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

“…[5][6][7] Other studies have evaluated the effects of steroids on the biophysical profile; these studies have revealed reductions in fetal movement, breathing, or amniotic fluid index (AFI), resulting in decreased biophysical profile scores. 8,9 The present study investigated the unanticipated effects of betamethasone on fetomaternal blood flow and AFI.…”

Section: Introductionmentioning

confidence: 99%

Effects of betamethasone on fetoplacental and maternal hemodynamics in preterm pregnancies

İnan

Sayın

Dolgun

et al. 2018

Intl J Gynecology & Obste

View full text Add to dashboard Cite

show abstract

“…A reactive nonstress test result provides reassurance of fetal well‐being; however, when abnormal, it has a high false‐positive rate of 45% to 75% 9 – 11 . The fetal heart rate is subject to various dynamic factors, including periodic sleep cycles, medications, and antenatal corticosteroids 12 , 13 . Further evaluation is needed to differentiate between the hypoxic or acidemic fetus versus the sleeping or medicated fetus.…”

Section: Discussionmentioning

confidence: 99%

Antenatal Surveillance in Twin Pregnancies Using the Biophysical Profile

Booker

Fox

Gupta

et al. 2015

J of Ultrasound Medicine

View full text Add to dashboard Cite

Objectives The nonstress test is currently the most widely used modality for antenatal surveillance in twin pregnancies, with a quoted false‐positive rate of 11%–12%. Our objective was to report our experience with the sonographic portion of the biophysical profile in twin pregnancies as the primary screening modality. Methods Women with twin pregnancies delivered by a single maternal‐fetal medicine practice from 2005 to 2013 were included. We excluded monoamniotic twins. Twin pregnancies began weekly sonography for the biophysical profile starting at 32 to 33 weeks, or earlier if indicated. The nonstress test was performed if the sonographic biophysical profile score was less than 8 of 8. We reviewed biophysical profile scores and outcomes for all patients who delivered at 33 weeks or later to assess the false‐positive rate for the biophysical profile, as well as the incidence of intrauterine fetal death (IUFD) after initiation of antenatal surveillance. Results A total of 539 twin pregnancies were included. The incidence of IUFD per patient was 2 per 539 (0.4%; 95% confidence interval [CI], 0.1%–1.3%), and the incidence of IUFD per fetus was 2 per 1078 (0.19%; 95% CI, 0.05%–0.7%). The overall positive screen rate was 24 per 539 (4.45%; 95% CI, 3.0%–6.5%). The false‐positive screen rate, defined as an abnormal biophysical profile that did not diagnose an IUFD or lead to delivery, was 10 per 539 (1.9%; 95% CI, 1.0%–3.4%). Conclusions—In twin pregnancies the use of the sonographic biophysical profile for routine antenatal surveillance has a low false‐positive rate, with a very low incidence of IUFD. The sonographic biophysical profile should be considered as a primary mode for antenatal surveillance in twin pregnancies, with a reflex nonstress test for an abnormal score.

show abstract

The effect of glucocorticosteroid administration on fetal movements and biophysical profile scores in normal pregnancies

Cited by 26 publications

References 8 publications

Decreased fetal movements: background, assessment, and clinical management

Decreased fetal movements: background, assessment, and clinical management

Effects of betamethasone on fetoplacental and maternal hemodynamics in preterm pregnancies

Antenatal Surveillance in Twin Pregnancies Using the Biophysical Profile

Contact Info

Product

Resources

About