“…The blood flow in the umbilical artery did not change in our study. This finding is similar to that of Baumann et al (1990), Lindblad et al (1987) and Veille et al (1988), although Giles et al (1987) and Marx et al (1986) found a decrease in resistance in the umbilical artery.…”
Section: Discussionsupporting
confidence: 87%
“…Our results are similar to those described by Baumann et al (1990) who used a pulsed Doppler technique to show an increase in RI and PI in the uteroplacental blood flow velocity waveforms after epidural anaesthesia for caesarean section, suggesting possible impairment of uteroplacental perfusion. However, Giles et al (1987), using continuous Doppler techniques, suggested a decrease in resistance and Long et al (1988) could not detect any changes in the PI. Using the 133 Xe washout method, Jouppila et al (1978) found a slight (but non‐significant) reduction in intervillous blood flow and no change in myometrial blood flow.…”
Section: Discussionmentioning
confidence: 86%
“…Lindblad et al (1987) found no changes in volume blood flow in the fetal descending aorta or in the umbilical vein. Giles et al (1987) demonstrated a decrease in resistance in the fetal and uteroplacental circulations. These findings could not be confirmed for the uteroplacental circulation by Long et al (1988) or for the umbilical circulation by Veille et al (1988).…”
“…The blood flow in the umbilical artery did not change in our study. This finding is similar to that of Baumann et al (1990), Lindblad et al (1987) and Veille et al (1988), although Giles et al (1987) and Marx et al (1986) found a decrease in resistance in the umbilical artery.…”
Section: Discussionsupporting
confidence: 87%
“…Our results are similar to those described by Baumann et al (1990) who used a pulsed Doppler technique to show an increase in RI and PI in the uteroplacental blood flow velocity waveforms after epidural anaesthesia for caesarean section, suggesting possible impairment of uteroplacental perfusion. However, Giles et al (1987), using continuous Doppler techniques, suggested a decrease in resistance and Long et al (1988) could not detect any changes in the PI. Using the 133 Xe washout method, Jouppila et al (1978) found a slight (but non‐significant) reduction in intervillous blood flow and no change in myometrial blood flow.…”
Section: Discussionmentioning
confidence: 86%
“…Lindblad et al (1987) found no changes in volume blood flow in the fetal descending aorta or in the umbilical vein. Giles et al (1987) demonstrated a decrease in resistance in the fetal and uteroplacental circulations. These findings could not be confirmed for the uteroplacental circulation by Long et al (1988) or for the umbilical circulation by Veille et al (1988).…”
“…Prior investigations have reported a reduction in uterine blood flow resistance as measured using Doppler velocimetry following epidural analgesia. 33, 34 It is plausible that this effect may improve uteroplacental hemodynamics among women with preeclampsia resulting in improved maternal support of the fetus during labor induction. However, this retrospective investigation is certainly limited in its ability to suggest causation for this effect.…”
OBJECTIVE
The objective of this investigation was to evaluate the effect of maternal obesity, as measured by prepregnancy body mass index (BMI), on the mode of delivery in women undergoing indicated induction of labor for preeclampsia.
STUDY DESIGN
Following IRB approval, patients with preeclampsia who underwent an induction of labor from 1997–2007 were identified from a perinatal information database, which included historical and clinical information. Data analysis included bivariable and multivariable analyses of predictor variables by mode of delivery. An artificial neural network was trained and externally validated to independently examine predictors of mode of delivery among women with preeclampsia.
RESULTS
Six hundred and eight women met eligibility criteria and were included in this investigation. Based on multivariable logistic regression (MLR) modeling, a five unit increase in BMI yields a 16% increase in the odds of cesarean delivery. An artificial neural network trained and externally validated confirmed the importance of obesity in the prediction of mode of delivery among women undergoing labor induction for preeclampsia.
CONCLUSION
Among patients who are affected by preeclampsia, obesity complicates labor induction. The risk of cesarean delivery is enhanced by obesity, even with small increases in BMI. Prediction of mode of delivery by an artificial neural network performs similar to MLR among patients undergoing labor induction for preeclampsia.
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