The effect of electrospinning parameters on the compliance behavior of electrospun polyurethane tube for artificial common bile duct

Moazeni, Najmeh; Semnani, Dariush; Rafeinia, Mohammad; Hasani, Hossein; Naeimi, Mitra; Sadrjahani, Mehdi

doi:10.1134/s0965545x17010114

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…The researchers used poly ( l -lactide-co-glycolide) (PLGA) nanofiber membranes prepared by electrospinning, which supported the adhesion and growth of L929 fibroblasts, as evidenced by scanning electron microscopy (SEM). However, the in vivo biocompatibility and appropriate biomechanical testing of these nanomaterial artificial bile ducts requires verification [ 32 ].…”

Section: Materials Choice For Artificial Bile Ductsmentioning

confidence: 99%

Progress and Current Limitations of Materials for Artificial Bile Duct Engineering

et al. 2021

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Bile duct injury (BDI) and bile tract diseases are regarded as prominent challenges in hepatobiliary surgery due to the risk of severe complications. Hepatobiliary, pancreatic, and gastrointestinal surgery can inadvertently cause iatrogenic BDI. The commonly utilized clinical treatment of BDI is biliary-enteric anastomosis. However, removal of the Oddi sphincter, which serves as a valve control over the unidirectional flow of bile to the intestine, can result in complications such as reflux cholangitis, restenosis of the bile duct, and cholangiocarcinoma. Tissue engineering and biomaterials offer alternative approaches for BDI treatment. Reconstruction of mechanically functional and biomimetic structures to replace bile ducts aims to promote the ingrowth of bile duct cells and realize tissue regeneration of bile ducts. Current research on artificial bile ducts has remained within preclinical animal model experiments. As more research shows artificial bile duct replacements achieving effective mechanical and functional prevention of biliary peritonitis caused by bile leakage or obstructive jaundice after bile duct reconstruction, clinical translation of tissue-engineered bile ducts has become a theoretical possibility. This literature review provides a comprehensive collection of published works in relation to three tissue engineering approaches for biomimetic bile duct construction: mechanical support from scaffold materials, cell seeding methods, and the incorporation of biologically active factors to identify the advancements and current limitations of materials and methods for the development of effective artificial bile ducts that promote tissue regeneration.

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Section: Materials Choice For Artificial Bile Ductsmentioning

confidence: 99%

Progress and Current Limitations of Materials for Artificial Bile Duct Engineering

et al. 2021

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“…Besides planar nanofibrous layers, various structures prepared from nanofibers are being used as well. Example of these structures are tubes, that find applications mostly as vascular replacements [1][2][3][4][5][6] because electrostatic spinning allows the direct preparation of grafts of less than 6 mm in diameter which is very hard to achieve by common methods. Other potential application is their use as scaffolds for vascular tissue regeneration.…”

Section: Introductionmentioning

confidence: 99%

Effect of different emitter types on the production of nanofibrous tubular structures: Thickness uniformity and productivity

et al. 2019

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“…One way to circumvent this problem is to add one heating step to partly fuse the layers [34]. Other fabrication routes for 3D electrospun fibers are: electrospinning directly on a 3D auxiliary template, post-processing of the fibers, and direct self-assembly of the polymer fibers [35][36][37][38]. Examples of 3D auxiliary templates can include tubular collector or 3D printed scaffold [39,40].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of radially aligned electrospun nanofibers in a three-dimensional conical shape

Vong¹,

Radacsi²

2018

Electrospinning

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This paper reports on the rapid fabrication of radially-aligned, three-dimensional conical structures by electrospinning. Three different polymers, Polyvinylpyrrolidone, Polystyrene and Polyacrylonitrile were used to electrospin the cones. These cone structures are spreading out from a vertical conductive pillar, which can be arbitrarily placed on specific part of the collector. The lower part of the cone is clearly defined on the collector, and the cone has a relatively uniform radius around the pillar. The cones are constituted of fibers that are radially aligned towards the top of the pillar, but there is no apex and the fibers fall flat on the top of the pillar surface. A parametric study has been performed to investigate the effects of the pillar morphology (height and thickness) and the electrospinning parameters (applied voltage and working distance) on the overall shape and size of the cone structure, as well as the fiber alignment. The pillar morphology influences directly the cone diameter and height. The electrospinning parameters have little effect on the cone structure. The formation mechanism has been identified to be related to the shape of the electric field, which has been systematically simulated to understand the effect of the electric field lines on the final dimensions of the cone structure.

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The effect of electrospinning parameters on the compliance behavior of electrospun polyurethane tube for artificial common bile duct

Cited by 4 publications

References 24 publications

Progress and Current Limitations of Materials for Artificial Bile Duct Engineering

Progress and Current Limitations of Materials for Artificial Bile Duct Engineering

Effect of different emitter types on the production of nanofibrous tubular structures: Thickness uniformity and productivity

Fabrication of radially aligned electrospun nanofibers in a three-dimensional conical shape

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