The effect of different methods of cross-linking of collagen on its dielectric properties

Marzec, E.; Pietrucha, Krystyna

doi:10.1016/j.bpc.2007.10.012

Cited by 39 publications

(26 citation statements)

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“…It can be associated with the dipolar relaxation process, most probably due to the changes located at interfaces [19]. This behavior was also observed by Marzec and Pietrucha [20], when they studied the effect of different methods of collagen cross-linking on its dielectric properties as a function of the temperature.…”

Section: Resultssupporting

confidence: 57%

New ferrimagnetic biocomposite film based in collagen and yttrium iron garnet

Figueiró¹,

Mallmann²,

Góes³

et al. 2010

Express Polym. Lett.

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In recent years a great interest in the study of the association of magnetic with biological material for bioapplications has been observed in the literature. This work analyses the development of new magnetic biocomposite films from a magnetic ferrite and a biopolymer. Magnetic and dielectric properties of Y3Fe5O12 (YIG)/collagen composite films were studied as a function of the YIG concentration. This biocomposite was also characterized by Infrared Spectroscopy (IR), Thermal Analysis (DSC and TG) and scanning electron microspcopic (SEM) methods. The magnetization and dielectric measurements were performed at room temperature. The results demonstrated that ferrimagnetic garnet (YIG) and collagen (Col) can be used to obtain a homogeneous composite. All the composite films showed a ferromagnetic behavior and they were characterized as a soft magnet material. These results show that Col-YIG biocomposites are biological films with magnetic properties that can be employed as a versatile performance materials, due to their flexible dielectric and magnetic features. They could be used as electronic devices in biological applications

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Section: Resultssupporting

confidence: 57%

New ferrimagnetic biocomposite film based in collagen and yttrium iron garnet

Figueiró¹,

Mallmann²,

Góes³

et al. 2010

Express Polym. Lett.

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“…For example, DHT and EDC has been used in combination to further enhance the mechanical properties of collagen and collagen-based scaffolds over either technique alone. 48 Crosslinking provides collagen scaffolds with an additional benefit, because by varying the degree of crosslinking present in and between collagen molecules, it is possible to control the rate of in vivo degradation. 19,49,50 Ideally, scaffolds should be designed with a slow enough degradation rate in order to maintain mechanical viability long enough to facilitate and support cell activity during the remodeling process.…”

Section: Dehydrothermal Processingmentioning

confidence: 99%

Collagen scaffolds for orthopedic regenerative medicine

Cunniffe

O’Brien

2011

JOM

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How would you……describe the overall signifi cance of this paper?Collagen and collagen-based scaffolds offer distinct advantages when selected as biomaterials for use across a broad spectrum of regenerative medicine applications. However, relatively poor mechanical properties are often perceived to limit their usefulness for orthopedic applications. These problems can be overcome through enhanced crosslinking mechanisms or through the addition of a second, stiffer phase such as hydroxyapatite, thus allowing tailored composite scaffolds to meet specifi c tissue requirements. This overview will highlight the current state of the art of these scaffolds, and consider the exciting prospects and future directions of collagen-based technologies for orthopedic regenerative medicine.…describe this work to a materials science and engineering professional with no experience in your technical specialty?Disease, injury and trauma can cause damage and degeneration of tissues and organs in the human body, which requires treatments to facilitate their repair, replacement or regeneration. Tissue engineering aims to regenerate damaged tissues instead of replacing them, by implanting biological substitutes that restore, sustain, or improve tissue function. Tissue engineering relies considerably on the use of porous 3-D scaffolds to provide a suitable environment for the regeneration of tissues and organs. These scaffolds essentially provide a template for new tissue formation and are either seeded with cells prior to implantation or are implanted directly into the injured site and the body's own cells populate the construct to facilitate healing. This review article focuses on the use of collagen and collagen-based scaffolds for tissue engineering applications. Overview biomaterials for regenerative medicineCollagen and collagen-based scaffolds offer distinct advantages when selected as biomaterials for use across a broad spectrum of regenerative medicine applications. However, relatively poor mechanical properties are often perceived to limit their usefulness for orthopedic applications. These problems can be overcome through enhanced crosslinking mechanisms or through the addition of a second, stiffer phase such as hydroxyapatite, thus allowing tailored composite scaffolds to meet specifi c tissue requirements. This overview will highlight the current state of the art of these scaffolds, and consider the exciting prospects and future directions of collagen-based technologies for orthopedic regenerative medicine.

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“…Thus, all the plots show the plasticizing effect of water on the b-relaxation temperature. Similar influence of water on the dielectric properties of collagen [16] and amorphous polymers [18,19] has also been reported. Figs.…”

Section: Methodsmentioning

confidence: 60%

“…Preliminary heating was performed to rid the samples of water excess. The procedure was also applied in our earlier studies on dielectric properties of some other biological materials [16].…”

Section: Methodsmentioning

confidence: 99%