1986
DOI: 10.1016/0163-7827(86)90028-7
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The effect of dietary ω3 and ω6 polyunsaturated fatty acids on gestation, parturition and prostaglandin E2 in intrauterine tissues and the kidney

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Cited by 21 publications
(8 citation statements)
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“…We take the opportunity to direct the attention towards a recent report that rats receiving standard rat chow supplemented with fish oil had longer gestation than when the standard rat chow was supplemented with arachis oil (Olsen et al 1990). This is a finding that is quite different from the rat studies cited by Dr Broughton Pipkin (Leat & Northrop 1979; Leaver et al 1986) where fish oil in both cases was supplemented to a linoleate‐deficient‐diet, and where the prolonged gestation could be due to the n‐3 fatty acids added as well as to the (absolute) lack of n‐6 fatty acids (indeed, the latter may well explain their findings of prolonged labour).…”
contrasting
confidence: 66%
“…We take the opportunity to direct the attention towards a recent report that rats receiving standard rat chow supplemented with fish oil had longer gestation than when the standard rat chow was supplemented with arachis oil (Olsen et al 1990). This is a finding that is quite different from the rat studies cited by Dr Broughton Pipkin (Leat & Northrop 1979; Leaver et al 1986) where fish oil in both cases was supplemented to a linoleate‐deficient‐diet, and where the prolonged gestation could be due to the n‐3 fatty acids added as well as to the (absolute) lack of n‐6 fatty acids (indeed, the latter may well explain their findings of prolonged labour).…”
contrasting
confidence: 66%
“…Evidence from previous studies supports our finding that dietary n ‐6 PUFAs have the ability to alter gestation length. Rats with n ‐6 PUFA deficiency have depressed PG synthesis and increased gestation length (Leaver et al 1986). Women undergoing preterm labour had raised concentrations of AA in erythrocytes in comparison with those delivering at full term (Reece et al 1997; Araya et al 1998).…”
Section: Discussionmentioning
confidence: 99%
“…14 This is in line with the results of studies on rats, where administering fish oil in pregnancy consistently results in reduced birth weight. [15][16][17] As far as we are aware this relation has not yet been examined in an English population. In this study we examine the relation between fish intake and pregnancy outcome in a large cohort of women in south west England.…”
mentioning
confidence: 97%