The effect of combined inhalation aromatherapy with lemon and peppermint on nausea and vomiting of pregnancy: A double-blind, randomized clinical trial

Safajou, Farzaneh; Soltani, Narges; Taghizadeh, Mohsen; Amouzeshi, Zahra; Sandrous, Maryam

doi:10.4103/ijnmr.ijnmr_11_19

Cited by 14 publications

(6 citation statements)

References 21 publications

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“…Safajou et al investigated the effect of inhaled aromatherapy with a combination of lemon and peppermint essential oils on nausea, vomiting, and fatigue among pregnant women. The results showed that aromatherapy reduced nausea and vomiting but had no effect on fatigue [ 32 ]. Blackburn et al evaluated the effect of inhalation aromatherapy with three essential oils of mint, lavender, and chamomile on the fatigue levels of 50 patients with leukemia.…”

Section: Discussionmentioning

confidence: 99%

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Comparing the Effect of Aromatherapy with Peppermint and Lavender Essential Oils on Fatigue of Cardiac Patients: A Randomized Controlled Trial

Mahdavikian

Fallahi

Khatony

2021

Evidence-Based Complementary and Alternative Medicine

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Background and Objectives. There is limited and contradictory evidence about the effect of aromatherapy with peppermint and lavender essential oils on the fatigue of cardiac patients. Therefore, the present study was aimed to compare the effect of aromatherapy with peppermint and lavender essential oils on fatigue in cardiac patients. Methods. This randomized controlled clinical trial was conducted on 105 cardiac patients. They were randomly divided into three groups: peppermint essential oil (n = 35), lavender essential oil (n = 35), and control (n = 35). Fatigue Severity Scale (FSS) was used to collect data. The intervention was performed for 7 nights. Before and after the intervention, the questionnaire was completed by all patients. In each intervention group, patients inhaled 3 drops of lavender or peppermint essential oils. In the control group, patients inhaled 3 drops of aromatic placebo. Results. The results showed the average fatigue decreased in the study groups. There was no statistically significant difference between the two groups of lavender and peppermint in terms of mean fatigue after the intervention. However, there was a statistically significant difference between lavender and control groups ( P < 0.001 ), as well as peppermint and control groups ( P < 0.001 ). Conclusion. Aromatherapy with peppermint and lavender essential oils can reduce the fatigue of cardiac patients, so the use of these fragrances is recommended.

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Section: Discussionmentioning

confidence: 99%

“…In the control group, the same amount of aromatic placebo was used. For this purpose, a very small amount of lavender essential oil (as plenty as micrograms) was added to the propylene glycol solution to create a sense of aromatic substances [ 32 ].…”

Section: Methodsmentioning

confidence: 99%

Comparing the Effect of Aromatherapy with Peppermint and Lavender Essential Oils on Fatigue of Cardiac Patients: A Randomized Controlled Trial

Mahdavikian

Fallahi

Khatony

2021

Evidence-Based Complementary and Alternative Medicine

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“…Ambos os grupos foram treinados para colocar três gotas da solução em uma bola de algodão e mantê-la a 3 cm afastada do nariz. Feito isso, a intensidade de náuseas, vômito e fadiga foi avaliada por meio do questionário de (PUQE-24) e Escala de Gravidade de Fadiga (FSS) (SAFAJOU et al, 2020).…”

Section: Efeitos Positivos Sobre Náuseas E Vômitosunclassified

“…Escores médios e desvios padrões (DP) de intensidade de vômitos e náuseas antes da intervenção e no primeiro dia de intervenção não foram tão significativamente diferentes entre os dois grupos, mas tornaram-se significativos no segundo, terceiro e quarto dias de intervenção com os óleos essenciais. Os resultados mostraram que o efeito do tempo na intensidade média de vômitos e náuseas foi significativo no grupo de aromaterapia (f= 2,84 = 22,92, p <0,001), mas não foi significativo no grupo de placebo que não recebeu o óleo essencial (f 2,78 = 0,26, p = 0,836) (SAFAJOU et al, 2020).…”

Section: Efeitos Positivos Sobre Náuseas E Vômitosunclassified

Evidências Científicas Sobre O Uso Da Aromaterapia Frente Aos Desconfortos Gestacionais

Silva¹,

Brito²,

Matos³

et al. 2022

Amplamente: Relatos E Pesquisa Em Saúde

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Todos os autores desta obra declaram que trabalharam ativamente na produção dos seus trabalhos, desde o planejamento, organização, criação de plano de pesquisa, revisão de literatura, caracterização metodológica, até mesmo na construção dos dados, interpretações, análises, reflexões e conclusões. Assim como, atestam que seus artigos não possuem plágio acadêmico, nem tampouco dados e resultados fraudulentos. Os autores também declaram que não possuem interesse comercial com a publicação do artigo, objetivando apenas a divulgação científica por meio de coletâneas em temáticas específicas.

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“…Aromatherapy is the inhalation of vaporised substances to alleviate symptoms. Various aromatherapies have been recommended for the treatment of nausea [ 19 , 20 ]. Isopropyl alcohol (IPA), the active component of cleaning alcohol wipes commonly found in clinical settings, is one such substance [ 21 – 23 ].…”

Section: Introductionmentioning

confidence: 99%

Isopropyl alcohol inhalation versus 5-HT3 antagonists for treatment of nausea: a meta-analysis of randomised controlled trials

Kimber,

Kovoor,

Glynatsis

et al. 2023

Eur J Clin Pharmacol

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Purpose Nausea is a common and unpleasant sensation for which current therapies such as serotonin (5-HT3) antagonists are often ineffective, while also conferring a risk of potential adverse events. Isopropyl alcohol (IPA) has been proposed as a treatment for nausea. We aimed to compare IPA with 5-HT3 antagonists for the treatment of nausea across all clinical settings. Methods MEDLINE, EMBASE, PubMed, CENTRAL and CINAHL were searched from inception to 17 July 2023 for randomised controlled trials (RCTs) comparing inhaled IPA and a 5-HT3 antagonist for treatment of nausea. Severity and duration of nausea, rescue antiemetic use, adverse events and patient satisfaction were the outcomes sought. Risk of bias (RoB) was assessed using Cochrane RoB 2. Random-effects model was used for meta-analysis. Combination of meta-analyses and narrative review was used to synthesise findings. The evidence was appraised using GRADE. Results From 1242 records, 4 RCTs were included with 382 participants. Participants receiving IPA had a significantly lower mean time to 50% reduction in nausea (MD − 20.06; 95% CI − 26.26, − 13.85). Nausea score reduction at 30 min was significantly greater in the IPA group (MD 21.47; 95% CI 15.47, 27.47). IPA led to significantly reduced requirement for rescue antiemetics (OR 0.60; 95% CI 0.37, 0.95; p = 0.03). IPA led to no significant difference in patient satisfaction when compared with a 5-HT3 antagonist. The overall GRADE assessment of evidence quality ranged from very low to low. Conclusion IPA may provide rapid, effective relief of nausea when compared with 5-HT3 antagonists.

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The effect of combined inhalation aromatherapy with lemon and peppermint on nausea and vomiting of pregnancy: A double-blind, randomized clinical trial

Cited by 14 publications

References 21 publications

Comparing the Effect of Aromatherapy with Peppermint and Lavender Essential Oils on Fatigue of Cardiac Patients: A Randomized Controlled Trial

Comparing the Effect of Aromatherapy with Peppermint and Lavender Essential Oils on Fatigue of Cardiac Patients: A Randomized Controlled Trial

Evidências Científicas Sobre O Uso Da Aromaterapia Frente Aos Desconfortos Gestacionais

Isopropyl alcohol inhalation versus 5-HT3 antagonists for treatment of nausea: a meta-analysis of randomised controlled trials

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