Abstract:The objective of this study was to investigate the relationship between coffee consumption 12 and obesity in Korean women. We included 5,995 women who participated in a health screening 13 examination at the Korean National Cancer Center between 2007 and 2016. Daily coffee 14 consumption was evaluated using the food frequency questionnaire. Obesity was assessed by body 15 mass index (BMI), and abdominal obesity was assessed by waist circumference (WC). A multiple 16 logistic regression model was used to calculate the odds ratio (OR) of obesity according to coffee 17 consumption. After multivariate adjustment, high coffee consumption was positively associated 18 with obesity measured by BMI (≥ 3 cups vs. no drinks, OR = 2.52; 95% confidence interval (CI) = 19 1.91-3.34; P for the trend < 0.001) and abdominal obesity measured by WC (≥ 3 cups vs. no drinks, 20 OR = 2.11; 95% CI = 1.59-2.79; P for the trend < 0.001). The positive association between daily coffee 21 consumption and obesity prevalence was not altered by menopause. The amount of coffee 22 consumed per day by Korean women was positively correlated with the prevalence of obesity, but 23 the mechanism underlying this phenomenon remains to be elucidated. 24