The effect of biannual applications of amine fluoride solution on caries incidence in permanent first molars: a 5‐year study

Abstract

A randomized double-blind clinical trial was undertaken in a nonfluoridated community to assess the effectiveness of a minimal preventive intervention based on biannual applications of an amine fluoride (AmF) solution containing 1% fluoride. A total of 284 schoolchildren aged 6 years were recruited from a primary school in Milan, Italy, and randomly assigned to an experimental or a control group. The subjects of the experimental group received two applications each year of AmF to the permanent first molars and the control group subjects received similar applications of a placebo solution. Both in the experimental and control groups caries experience (DMFT) of the first molars was recorded every 6 months for 5 years. The mean DMFT scores in the experimental and control group were, respectively, 0.56 and 0.22 at the beginning and 1.14 and 1.75 at the end of the study. The preventive effect of the treatment became statistically significant only after 3 years. Survival analysis performed on the first molars that were sound at baseline showed that the topical AmF treatment caused, after 5 years, a significant reduction of caries incidence. This result confirms observations found in the international literature on the anticaries action of AmF. The administration rate used in this study seems to be useful for community preventive applications as it reduces the total amount of fluoride administered and the potential risks, and involves few personnel.

Caries Incidence in Children of Primorsko Goranska County, Croatia

“…Better results for dft were shown in a Greek study, but the same study presents DMFT of 1.35 [21]. A similar increase is present in certain Italian study [22]. The drop of DMFT values was reported by some other studies from: Scotland, Ireland, Poland and Finland.…”

Caries Epidemiology and Community Dentistry: Chances for Future Improvements in Caries Risk Groups. Outcomes of the ORCA Saturday Afternoon Symposium, Greifswald, 2014. Part 1

“…Even 2 applications of fluoride gels, fluids or varnishes per year resulted in up to 60% reduction of caries incidence [Brambilla et al, 1997;van Rijkom et al, 1998;Marinho et al, 2002aMarinho et al, , b, 2003]. Fluoridated domestic salt, the cheapest measure of all, has been recommended in Switzerland (83% market share since 2000) and Germany (53% market share in 2002) [Marthaler, 2003].…”

Feeding Pattern Effect on Oral Health Parameters and Salivary Il-6 Level Among Preschool Children

“…The antagonistic balance between the oral microbiota and the immune defense system produces the physiological composition of the oral environment. Oral inflammatory diseases are thought to form because of a changed relationship between potential pathogenicity, self-healing capacity, and immune defense [4]. Dental caries has been a widespread illness in the neighborhood for many years.…”