2024
DOI: 10.2174/1566524023666220819140748
|View full text |Cite
|
Sign up to set email alerts
|

The Effect of Bacterial Composition Shifts in the Oral Microbiota on Alzheimer's Disease

Abstract: Alzheimer's disease (AD), a neurological disorder, despite significant advances in medical science, has not yet been definitively cured, and the exact causes of the disease remain unclear. Due to the importance of AD in the clinic, large expenses are spent annually to deal with this neurological disorder, and neurologists warn of an alarm to increase this disease in the elderly people in the near future. It has been believed that microbiota dysbiosis lead to Alzheimer’s as a multi-step disease. In this regard,… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
4

Relationship

1
3

Authors

Journals

citations
Cited by 4 publications
(3 citation statements)
references
References 127 publications
0
3
0
Order By: Relevance
“…16S rRNA gene was utilized as a normalizing factor. To analyze the relative changes in gene expression ports, the 2 − ΔΔCt method was applied 41 .…”
Section: Methodsmentioning
confidence: 99%
“…16S rRNA gene was utilized as a normalizing factor. To analyze the relative changes in gene expression ports, the 2 − ΔΔCt method was applied 41 .…”
Section: Methodsmentioning
confidence: 99%
“…16 S rRNA gene was utilized as a normalizing factor. To analyze the relative changes in gene expression ports, the 2ΔΔCt ${2}^{-\mathrm{\Delta \Delta }{C}_{{\rm{t}}}}$ method was applied [35].…”
Section: Methodsmentioning
confidence: 99%
“…By reducing the number of species targeted by bacteriophage, the population of nontarget species is balanced, but there is an inherent risk that these species will become resistant to phages. A genetically modified phage, however, was an appropriate strategy for balancing the composition of the microbiota communities (Gibb et al, 2021; Hsu et al, 2019; Moghadam, Bakhshayesh, et al, 2022; Taati Moghadam et al, 2022). By disrupting the biofilm mechanism, bacteria can become multicellular, attached to various surfaces, including living tissues, medical devices, food, water pipes, and industrial equipment by an extracellular matrix polysaccharide.…”
Section: Phage Engineered Phage and Phage Enzymesmentioning
confidence: 99%