The effect of ascogen on the immune response of Tilapia fish to Aeromonas hydrophila vaccine

Dietary oligonucleotides from yeast RNA influence immune responses and resistance of hybrid striped bass (Morone chrysops × Morone saxatilis) to Streptococcus iniae infection

“…They hypothesized that dietary nucleotides are capable of enhancing the potential of the immune system in general to mount greater and more rapid specific responses, as compared to the primarily non-specific capacity of phagocytes induced by glucan. This hypothesis was supported by other reports on Atlantic salmon [16] and hybrid tilapia [19] fed nucleotide-supplemented diets. Atlantic salmon were reported to have an enhanced efficacy of vaccination based on comparing antibody titers and survival rate [19].…”

“…This hypothesis was supported by other reports on Atlantic salmon [16] and hybrid tilapia [19] fed nucleotide-supplemented diets. Atlantic salmon were reported to have an enhanced efficacy of vaccination based on comparing antibody titers and survival rate [19]. Similarly, a marked rise in the geometric mean of antibody titers after vaccination was observed in tilapia [18].…”

“…In recent years, the beneficial influences of oral administration of nucleotides on immune functions, vaccine efficiency, or disease resistance have also been demonstrated in fish such as Atlantic salmon (Salmo salar) [16,17], coho salmon (Oncorhynchus kisutch) [16], rainbow trout (Oncorhynchus mykiss) [16], common carp (Cyprinus carpio) [18] and hybrid tilapia (Oreochromis niloticus ! Oreochromis aureus) [19]. However, information on hybrid striped bass is not available to date.…”

Efficacy of nucleotide related products on growth, blood chemistry, oxidative stress and growth factor gene expression of juvenile red sea bream, Pagrus major

“…Recently, in aquaculture research nucleotides and its related product has been paid attention promisingly as functional nutrients. In aquaculture dietary nucleotide and its related products supplementation has been shown to enhance growth of certain fish species (reviewed by Li and Gatlin, 2006) immune responses and disease resistance of all male hybrid tilapia (Saratheradon niloticus ♀ × Saratheradon aureus ♂ (Ramadan et al, 1994), Atlantic salmon (Salmo salar L.) (Burrells et al, 2001a), common carp (Cyprinus carpio L.) (Sakai et al, 2001), hybrid striped bass (Morone chrysops × Morone saxatilis) (Li et al, 2004), grouper (Epinephelus malabaricus) (Lin et al, 2009), red drums (Sciaenops ocellatus) (Cheng et al, 2011), rainbow trout (Oncorhynchus mykiss) (Tahmasebi-Kohyani et al, 2012) and Japanese flounder (Paralichthys olivaceus) (Song et al, 2012). Supplementation of nucleotides was also reported to increase stress tolerance in Atlantic salmon (Burrells et al, 2001b), rainbow trout (Leonardi et al, 2003), red sea bream (Hossain et al, 2016) and even gastrointestinal physiology and morphology of tilapia (Ramadan et al, 1994), Atlantic salmon (Burrells et al, 2001b) and red drum (Cheng et al, 2011).…”

Aquaculture Health Management: A new Approach

“…They play key roles in numerous essential physiologic functions, including encoding genetic information, mediating energy metabolism and signal transduction [84,85]. The beneficial influences of oral administration of nucleotides on immune functions, vaccine efficiency or disease resistance has also been demonstrated in fish such as Atlantic salmon, coho salmon, rainbow trout, common carp, hybrid tilapia and hybrid striped bass [86][87][88] reported beneficial effects of dietary nucleotides when challenging salmonids with infectious salmon anaemia virus, Vibrio anguillarum, Piscirickettsia salmonis and sea lice. They hypothesized that dietary nucleotides are capable of enhancing the potential of the immune system in general to mount greater and more rapid specific responses, as compared to the primarily nonspecific of phagocytes induced by glucan.…”