1978
DOI: 10.3181/00379727-158-40237
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The Effect of Altered Thyroid State on Prolactin Binding to Liver and 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Rats

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1979
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Cited by 10 publications
(11 citation statements)
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“…The present results confirm previous reports of the presence of specific binding sites for lactogenic hormones in the rat mammary gland (Kelly, Bradley, Shiu, Meites «fe Friesen, 1974;Reddy & Watkins, 1975;Holcomb et al 1976;Smith, Hilf «fe Senior, 1976;Bohnet, Gomez & Friesen, 1977). In this study prolactin binding was usually measured in a micro¬ somal fraction.…”
Section: Discussionsupporting
confidence: 92%
“…The present results confirm previous reports of the presence of specific binding sites for lactogenic hormones in the rat mammary gland (Kelly, Bradley, Shiu, Meites «fe Friesen, 1974;Reddy & Watkins, 1975;Holcomb et al 1976;Smith, Hilf «fe Senior, 1976;Bohnet, Gomez & Friesen, 1977). In this study prolactin binding was usually measured in a micro¬ somal fraction.…”
Section: Discussionsupporting
confidence: 92%
“…It was found that this receptor was present in much higher concentrations in female than male rats. These findings have been confirmed by other groups including our own (71)(72)(73)(74). The development of these receptors has been shown to follow that of the steroid-metabolizing enzymes rather closely.…”
Section: Central Control Of Prolactin (Pri) Receptors In the Liversupporting
confidence: 81%
“…Some previous studies (Costlow et al, 1976;Holdaway and Friesen, 1976;Kelly et al, 1974) suggested that changes in the growth of DMBA-induced mammary tumors following endocrine treatment may be reflected by changes in PRL binding to tumor cells. However, our study and others (DeSombre et al, 1976;Smith et al, 1976) …”
Section: Analysis Of Datacontrasting
confidence: 68%
“…These results may indicate regional heterogeneity of PRL receptors as previously reported (Smith et al, 1976) and a potential role of PRL in liver function which might affect mammary tumors through some growth factors (Francis and Hill, 1975) or enzyme modification (Richards, 1975). Some previous studies (Costlow et al, 1976;Holdaway and Friesen, 1976;Kelly et al, 1974) suggested that changes in the growth of DMBA-induced mammary tumors following endocrine treatment may be reflected by changes in PRL binding to tumor cells.…”
Section: Analysis Of Datasupporting
confidence: 67%
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