The effect of altered carbohydrate metabolism in pertussis-sensitized mice on anaphylaxis

Gulbenkian, A.; Grasso, A.; Tabachnick, I. I. A.

doi:10.1016/0006-2952(67)90051-2

Cited by 11 publications

(2 citation statements)

References 17 publications

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“…Normal mice similarly treated show a pronounced rise. Pertussis vaccine-treated mice and rats also fail to show the hyperglycemic response after release of endogenous epinephrine or after treatment with exogenous epinephrine (58,77,228). Moreover, epinephrine administered to HSF-treated mice does not reduce the tissue uptake of glucose (58).…”

Section: Various Changes Observed and Other Phenomena Associated Withmentioning

confidence: 99%

Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis.

Muñoz¹,

Bergman²

1968

Bacteriological Reviews

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a Toxicity = LD5so of histamine given intraperitoneally, expressed as milligrams of histamine base per kilogram of body weight. b J. Munoz, unpublished data. toxin. This reaction was most probably an anaphylactic shock, although it was not recognized as such by Ospeck and Roberts. Parfentjev et al. (186-188) observed a similar phenomenon when they found that mice pretreated with pertussis vaccine died after receiving a denatured nucleoprotein isolated from B. pertussis. This sensitivity was considered to have an immunological basis, but it was not clearly recognized as being associated with anaphylactic shock until Malkiel and Hargis described their observations on the increased susceptibility of B. pertussis-treated mice and rats to actively induced anaphylaxis (121-124). These observations have been confirmed and extended by various workers employing a variety of antigens (100, 154, 205, 223). Furthermore, B. pertussis-treated mice were also seen to become more susceptible to passively induced anaphylaxis (

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Section: Various Changes Observed and Other Phenomena Associated Withmentioning

confidence: 99%

Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis.

Muñoz¹,

Bergman²

1968

Bacteriological Reviews

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“…It has been known that epinephrine induced hyperglycemia is markedly at tenuated in pertussis-sensitized rats (1)(2)(3). This phenomenon has been explained by several investigators as a result of a selective i9-adrenergic receptor blockade by the pertussis vaccine (3)(4)(5).…”

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confidence: 99%

Potentiation of insulin secretory response of rats by BCG injection.

Kawata

Itaya

1982

Jpn.J.Pharmacol

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Abstract-Effectsof BCG cells on blood insulin, glucose, glycerol and free fatty acid (FFA), and liver glycogen were examined in rats in vivo. Freund's complete adjuvant (FCA) was used as a solution containing BCG cells. Insulin secretion and lactate production by isoproterenol were enhanced by FCA injection.Hyperglycemia induced by epinephrine was somewhat attenuated by treating rats with FCA. The increment of plasma FFA by isoproterenol was smaller in FCA-injected rats than that in control rats. The amount of glycogen in liver was increased by FCA treatment. Anti-insulin antiserum (AIS) did not modify the lactate producing action of isoproterenol.FFA release stimulated by isoproterenol was enhanced by AIS. Liver glycogen content in FCA-injected rats was decreased by AIS injection.These results suggest that some component(s) of BCG cells may enhance insulin release stimulated by secretagogues, and insulin thus released attenuates some metabolic effects of the agonist.

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Effect of epinephrine on hepatic glycogen phosphorylase and synthetase activities in normal and pertussis-sensitized rats

Kreutner¹,

Gulbenkian²,

Tabachnick³

1970

Biochemical Pharmacology

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The effect of altered carbohydrate metabolism in pertussis-sensitized mice on anaphylaxis

Cited by 11 publications

References 17 publications

Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis.

Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis.

Potentiation of insulin secretory response of rats by BCG injection.

Effect of epinephrine on hepatic glycogen phosphorylase and synthetase activities in normal and pertussis-sensitized rats

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