The effect of aloe vera gel on the anti-acne properties of the essential oil of Ocimum gratissimum Linn leaf – a preliminary clinical investigation

Orafidiya, Lara O.; Agbani, Ejaife O.; Oyedele, A. O.; Babalola, O. O.; Onayemi, O.; Aiyedun, F.F

doi:10.1016/j.ijat.2003.12.005

Cited by 43 publications

(30 citation statements)

References 25 publications

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“…It was found that Aloe vera gel enhanced the antiacne properties of Ocimum oil. The oil or its combination with aloe vera gel was found to be effective than 1% Clindamycin in the treatment of Acne vulgaris [68].…”

Section: Clinical Studiesmentioning

confidence: 95%

Ocimum gratissimum: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Prabhu¹,

Lobo²,

Shirwaikar³

2009

TOALTMEDJ

130

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Abstract:Ocimum gratissimum is a well-known plant used in the Indian system of medicine. Folklore medicine claims its use in headache, fever, diarrhoea, pneumonia etc. Research carried out using different in vitro and in vivo techniques of biological evaluation supports most of the claims. This review presents the ethnobotanical, natural product chemistry, pharmacological, clinical and toxicological data of the plant.

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Section: Clinical Studiesmentioning

confidence: 95%

Ocimum gratissimum: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Prabhu¹,

Lobo²,

Shirwaikar³

2009

TOALTMEDJ

130

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“…The result indicates that the efficacy of the Ocimum oil lotion products increased with increasing aloe gel contents. Products formulated with the undiluted or 50% aloe gels were most active and resolved inflammatory lesions faster than 1% Clindamycin in the treatment of Acne vulgaris (Orafidiya et al 2004). Preliminary evidence looks promising, but much work remains to be done to prove the values of anti-inflammatory herbs for acne.…”

Section: Antimicrobial Herbs For Acnementioning

confidence: 99%

Different approaches of alternative medicines in acne vulgaris treatment

Ghosh

Nagore

Kadbhane

et al. 2011

Orient Pharm Exp Med

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Acne vulgaris is common dermatological disorder primarily acts on children and adolescents. This affects approximately 80% of the population between the ages of 12-25 years. The clinically used anti-acne drugs suffer from the disadvantage of side effects and high cost of treatment. Alternative to these drugs are traditional medicines and natural products, which offer a great hope in the identification of bioactive lead compounds and their development into drugs for the treatment of skin disorder like acne vulgaris. The use of traditional medicines and phytopharmaceuticals for treating various skin ailments dates back several centuries. The aim of the present review is to compile relevant data on the mechanisms of action of various natural compounds from ethnomedicinal plants and their role in the resolution of acne vulgaris. An attempt is also being made to enumerate the possible leads from Indian traditional medicinal system for the treatment of acne. We tried to provide the readers with the array of outcome variables, which can be further worked upon in clinical studies. Finally, this paper puts forth issues that need to be addressed by researchers in the future.

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“…There is evidence for modest efficacy of tea tree oil Maleleuca alternifoloia in comedonal acne [40], gluconolactone in inflammatory and noninflammatory acne [41] and less rigorous evidence for essential oil of basil Ocimum gratissimum and Ocimum basilicum [42,43], Ayervedic herbal preparations [44] and oral gugulipid (an extract of Commiphora mukul) [45]. Oral zinc sulphate improved acne in several small randomized controlled trials [46][47][48] but has failed to do so in others [49,50].…”

Section: Cam In Acnementioning

confidence: 99%

Complementary and alternative medicines: use in skin diseases

Magin¹,

Adams²

2007

Expert Review of Dermatology

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There is a plethora of complementary and alternative medicines (CAM) used by sufferers of skin diseases. For the most part, the use of these therapies is based on anecdotal evidence or on traditional patterns of use. Relatively little empirical evidence exists for the use of CAM therapies in skin diseases. Those studies that have examined CAM skin disease therapies have often been flawed methodologically. A small number of CAM therapies have been accepted or are on the cusp of acceptance in dermatological practice. Even here, the evidence for CAM use is often limited or equivocal. Equally, issues of poorly documented adverse effect profiles, quality control of preparations and product adulteration and contamination hamper the integration of CAM therapies into orthodox dermatology practice. Thus, it may be more appropriate to consider 'pluralism' rather than 'integration' in the relationship of CAM and conventional medicine.

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The effect of aloe vera gel on the anti-acne properties of the essential oil of Ocimum gratissimum Linn leaf – a preliminary clinical investigation

Cited by 43 publications

References 25 publications

Ocimum gratissimum: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Ocimum gratissimum: A Review of its Chemical, Pharmacological and Ethnomedicinal Properties

Different approaches of alternative medicines in acne vulgaris treatment

Complementary and alternative medicines: use in skin diseases

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