The effect of adjuvant therapy for high intermediate-risk endometrial cancer on patients with recurrent disease

Doo, David W.; Essel, K.G.; Vetter, Monica Hagan; Machiorlatti, Michael; Evans, E.; Strope, B.; Vesely, Sara K.; Powell, Matthew A.; Salani, Ritu; Moore, Kathleen N.; Arend, Rebecca C.

doi:10.1016/j.ygyno.2019.03.120

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“…During the perimenopausal and postmenopausal periods, women are more likely to develop endometrial cancer. It is mainly treated by surgery in clinic [ 1 ]. Laparoscopic surgery has the advantages of high safety and less complications during the perioperative period.…”

Section: Introductionmentioning

confidence: 99%

Effects of Quantitative Nursing Combined with Psychological Intervention in Operating Room on Stress Response, Psychological State, and Prognosis of Patients Undergoing Laparoscopic Endometrial Cancer Surgery

Chen

Wang

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To investigate the effects of quantitative nursing and psychological interventions on stress response, mental health, and prognosis in endometrial cancer patients having laparoscopic surgery. Methods. The random number table approach was used to identify and split 98 patients with endometrial cancer undergoing laparoscopic surgery at our hospital’s Obstetrics and Gynecology Hospital ( n = 49 ) into observation and control groups ( n = 49 ) from May 2020 to February 2022. Both groups received standard care in the operating room, while those in the observation group received quantitative and psychological interventions in the operating room. Both groups were compared for perioperative markers, stress indicators, coping strategies, and pain levels. Results. In terms of age, TNM stage, or pathology, there was no statistically significant difference between the two groups ( P > 0.05 ). Both the observation and control groups experienced statistically significant ( P < 0.05 ) reductions in the perioperative markers of operation time, intraoperative blood loss, and overall hospital stay. Both groups’ SAS and SDS scores were lower than they had been prior to surgery, but the observation group had lower scores than the control group, and these differences were statistically significant ( P < 0.05 ). Postsurgery, the observation group’s cortisol and adrenaline levels were lower than those of the control group, and both groups’ levels were higher than before surgery, with statistical significance ( P < 0.05 ) in both groups. Neither coping style nor pain level differed significantly between the two groups before surgery ( P > 0.05 ). Postoperatively, while yield item scores were lower and faces scores were higher than the control group, the observation group’s avoidance item score was lower than the control group. All with statistical significance. There were substantial differences in NRS SCORE between observers and controls. Conclusion. After laparoscopic surgery to remove endometrial cancer, patients may benefit from the combination of quantitative nursing and psychological intervention in the operating room to alleviate postoperative anxiety and sadness and reduce stress reaction.

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Section: Introductionmentioning

confidence: 99%