Abstract:The concordance of UTI with blood group ARh+ may be due to the most seen of ARh+ phenotype in the investigated population. We suggest that before defining the relationships on genetical markers, it would be more reliable to correlate them with their local distributions in the population.
“…Many studies indicated a close relationship between ABO blood antigens and many diseases [24] [25] [26]. The relation of blood groups ABO with UTI found in many studies [27]. Our study with previous data [28] indicated blood groups ABO in relation to UTI depends on the epidemic region and bacterial genera.…”
Rheumatoid arthritis (RA) is a chronic disease associated with many factors, such as urinary tract infection (UTI), and the complicated type of UTI bacteria is Proteus mirabilis. Accordingly, 67 RA patients with UTI and 45 healthy controls from Baghdad regions were included in this study. Proteus mirabilis isolates were obtained from the urine of patients with RA and identified in 11.9% by biochemical tests and 16sRNA gene sequencing. ABO blood types, serum TNF-α level, serum rheumatoid factor (RF), C-reactive protein, and anti-bacterial antibody level of RA patients were compared to healthy controls. The study indicated that there is a correlation between blood type O, serum TNF-α level, rheumatoid factor (RF), C-reactive protein, and anti-bacterial antibody level of RA patients. The significant result was the increased serum level of TNF-α of RA patients who were infected with urease-produced bacteria, this might be due to the enzyme structure's role in evoking the disease.
“…Many studies indicated a close relationship between ABO blood antigens and many diseases [24] [25] [26]. The relation of blood groups ABO with UTI found in many studies [27]. Our study with previous data [28] indicated blood groups ABO in relation to UTI depends on the epidemic region and bacterial genera.…”
Rheumatoid arthritis (RA) is a chronic disease associated with many factors, such as urinary tract infection (UTI), and the complicated type of UTI bacteria is Proteus mirabilis. Accordingly, 67 RA patients with UTI and 45 healthy controls from Baghdad regions were included in this study. Proteus mirabilis isolates were obtained from the urine of patients with RA and identified in 11.9% by biochemical tests and 16sRNA gene sequencing. ABO blood types, serum TNF-α level, serum rheumatoid factor (RF), C-reactive protein, and anti-bacterial antibody level of RA patients were compared to healthy controls. The study indicated that there is a correlation between blood type O, serum TNF-α level, rheumatoid factor (RF), C-reactive protein, and anti-bacterial antibody level of RA patients. The significant result was the increased serum level of TNF-α of RA patients who were infected with urease-produced bacteria, this might be due to the enzyme structure's role in evoking the disease.
“…These findings may indicate the influence of A + and O + blood groups phenotypes on susceptibility to UT infection. 8 Comparing with the Turkish study, the ratios of this work are higher, indicating that the carriers of these blood groups are more susceptible within their ranges of ages (> 51)) for males and (10-30) for females. The variations between the ranges of ages of both males and females are related to anatomical factor ( the possibility of contamination because the urethra is very near to the vaginal wall and so women are more likely to get UT infection, or from sex act) or from the sexual intercourse and frequency of sex 17 , or other behavioral habits (not drinking enough fluids, cleanliness).…”
Section: Discussioncontrasting
confidence: 48%
“…First of all, we must refer to the congruence in the results of our study and those of the Turkish population. Both showed high proportions for people with UT infection who are holders of A + and O + blood groups distribution (36.6% and 31.7%, respectively in Turkish study 8 and 46.2% and 38.5%, respectively for the UTIs male patients of the current research). Knowing that the Turkish study was performed for patients as a mixed single group, while in this work a single group of females and another for males were used, separately.…”
Section: Discussionmentioning
confidence: 41%
“…Increased receptivity on the host cells has been suggested to influence proneness to infection. 8 There are several publications that define enhanced bacterial adhesions due to genetic markers such as blood group types 9 , and certain factors that facilitate the mechanism of attachment of E. coli . 11 It was worth to investigate the pH of the urinary tract content as one of these factors that may facilitate the bacterial attachment.…”
Background and objectives:The urinary tract infection (UTI) occurs in any part of the urinary system. Researches on bacterial adhesions were carried out due to the role of blood group types or the influence of numerous kinds of foods. This study is an attempt to investigate the role of these two factors. Methods: This work was conducted through; first; investigating the ABO-Rh group distribution of 103 patients with UTI, and second; detecting the optimal pH of the media that might facilitates the attachment of Escherichia coli (E. coli) to the lining mucosa layer. Results: 58.4% of females UTIs patients were between 10-30 years, and 53.9% of males were more than 51 years. The pH of urine in UTIs female patients was less than 7 and saliva pH was 7, whereas both in males were less than 7. Some acid-yielding and alkaline-yielding foods prevented the growth of E. coli. Neutral foods did not. Conclusions: Patients who are owners of A and O blood groups are more prone to infection at age 10-30 for females and males who are over 51 years. Read phonetically Dictionary -View detailed dictionaryThe pH of both urine and saliva in males and females were neutral and slightly acidic. Some acid and alkaline yielding foods prevented the growth of bacteria. Key words: urinary tract infection, ABO/Rh blood groups distribution, urine and saliva pH The urinary tract infection (UTI) occurs when bacteria begin to grow in the kidneys, the bladder, and the ureters.
The purpose of this paper was to report the burden and characteristics of infection by multidrug-resistant Pseudomonas aeruginosa (MDR-PA) in clinical samples from intensive care unit (ICU) adults, and to identify predictors. This was a retrospective observational study at four medical-surgical ICUs. The case cohort comprised adults with documented isolation of an MDR-PA strain from a clinical specimen during ICU stay. Multivariate analysis was performed to identify predictors for MDR-PA infection. During the study period, 5667 patients were admitted to the ICU and P. aeruginosa was isolated in 504 (8.8%). MDR-PA was identified in 142 clinical samples from 104 patients (20.6%); 62 (43.6%) of these samples appeared to be true infections. One hundred and eighteen (83.1%) isolates were susceptible only to amikacin and colistin, and 13 (9.2%) were susceptible only to colistin. Overall, the MIC to meropenem was 16 μg/mL and the MIC was >32 μg/mL, with 60.4% of respiratory samples being MIC >32 μg/mL to meropenem. Independent predictors for MDR-PA infection were fever/hypothermia [odds ratio (OR) 9.09], recent antipseudomonal cephalosporin therapy (OR 6.31), vasopressors at infection onset (OR 4.40), and PIRO (predisposition, infection, response, and organ dysfunction) score >2 (OR 2.06). This study provides novel information that may be of use for the clinical management of patients harboring MDR-PA and for the control of the spread of this organism.
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